Cystic lung lesion following transbronchial lung cryobiopsy: Case report and systematic review

Transbronchial lung cryobiopsy (TBLC) is a technique used to sample the lungs for diagnosing diffuse lung diseases. A sizeable tissue is sheared off the lung parenchyma during TBLC leading to a defect in the lung, which might result in a cystic lesion on imaging. Computed tomography (CT) performed f...

Full description

Saved in:
Bibliographic Details
Published in:Lung India 2023-05, Vol.40 (3), p.267-270
Main Authors: Malegaonkar, Srikant, Sehgal, Inderpaul, Muthu, Valliappan, Agarwal, Ritesh, Bal, Amanjit, Dhooria, Sahajal
Format: Article
Language:English
Subjects:
bronchoscopy
Case Report
Case reports
Cysts
Diagnosis
hypersensitivity pneumonitis
ild
interstitial lung disease
lung cryobiopsy
Lung diseases
Systematic review
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Transbronchial lung cryobiopsy (TBLC) is a technique used to sample the lungs for diagnosing diffuse lung diseases. A sizeable tissue is sheared off the lung parenchyma during TBLC leading to a defect in the lung, which might result in a cystic lesion on imaging. Computed tomography (CT) performed for other reasons might incidentally reveal such a cyst. We report a 75-year-old patient who underwent TBLC and developed significant intraprocedural bleeding. Chest CT performed for worsening breathlessness revealed an acute exacerbation (AE) of the underlying interstitial lung disease, and incidentally showed a new cyst in the biopsied lung lobe. The patient recovered clinically after the administration of high-dose methylprednisolone. A chest CT performed nine months later showed resolution of the lung cyst. A systematic review of the literature revealed that cysts/pneumatoceles/cavities may appear in 50% of patients following TBLC. About 90% are due to biopsy trauma and mostly resolve spontaneously. Rarely, a cavity may be due to infection; antimicrobial agents should be administered in such cases.
ISSN:0970-2113
0974-598X
DOI:10.4103/lungindia.lungindia_429_22