Plasmapheresis in neurological disorders: Experience from a tertiary care hospital in South India

Therapeutic plasma exchange (PE) or plasmapheresis is the treatment of choice in many neurological disorders. Even though it is safe in experienced hands, there is a major concern about its safety among physicians. To analyze our experience with 230 patients who underwent PE for various neurological...

Full description

Saved in:
Bibliographic Details
Published in:Annals of the Indian Academy of Neurology 2015-01, Vol.18 (1), p.15-19
Main Authors: Gafoor, V Abdul, Jose, James, Saifudheen, K, Musthafa, Mohamed
Format: Article
Language:English
Subjects:
Care and treatment
Continuous flow method
Guillain-Barré syndrome
Methods
Nervous system diseases
Neurological disorders
Original
Plasmapheresis
therapeutic plasma exchange
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c628t-f93e42b193f47ff477dc8099f1e2363cb72b445a629d55d0339630481c73439e3
cites
container_end_page 19
container_issue 1
container_start_page 15
container_title Annals of the Indian Academy of Neurology
container_volume 18
creator Gafoor, V Abdul
Jose, James
Saifudheen, K
Musthafa, Mohamed
description Therapeutic plasma exchange (PE) or plasmapheresis is the treatment of choice in many neurological disorders. Even though it is safe in experienced hands, there is a major concern about its safety among physicians. To analyze our experience with 230 patients who underwent PE for various neurological disorders. Retrospective review of PE procedures done during a period of 48 months, from July 2007 to June 2011 in a tertiary care teaching hospital in South India. Indications, clinical results and technical factors are discussed. The main indication for PE was GBS (203 patients; 88.3%). Age of patients ranged from 14-65 (mean = 42.3 years). The most common complications were paraesthesias and/or cramps (36.1%) and hypotension (32.2%). Four pregnant patients who underwent PE had good recovery with one intrauterine death. There was no mortality. The analysis of 240 cases of PE done in our department shows that the procedure is safe, with only minimal procedure related complications and no mortality.
doi_str_mv 10.4103/0972-2327.144301
format article
fullrecord <record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_ce21d5d320b143fdb17bc62126f70192</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A401163779</galeid><doaj_id>oai_doaj_org_article_ce21d5d320b143fdb17bc62126f70192</doaj_id><sourcerecordid>A401163779</sourcerecordid><originalsourceid>FETCH-LOGICAL-c628t-f93e42b193f47ff477dc8099f1e2363cb72b445a629d55d0339630481c73439e3</originalsourceid><addsrcrecordid>eNqFkt2LEzEUxQdR3Lr67pMM-OLL1HxOJj4Iy7JqYUFBfQ6Z5KZNmUlqMiP635tu12qlICEEknN-ufdyquo5RkuGEX2NpCANoUQsMWMU4QfVAkvZNZQz-bBaHJ8vqic5bxHiLaPt4-qCcME4RWxR6U-DzqPebSBB9rn2oQ4wpzjEtTd6qK3PMVlI-U1982MHyUMwULsUx1rXE6TJ6_SzNjpBvYl556fiKYzPcZ429SpYr59Wj5weMjy7Py-rr-9uvlx_aG4_vl9dX902piXd1DhJgZEeS-qYcGULazokpcNAaEtNL0jPGNctkZZziyiVbemgw0ZQRiXQy2p14Nqot2qX_FgqU1F7dXcR01rpUq4ZQBkg2HJLCeoxo872WPSlCkxaJxCWpLDeHli7uR_BGghT0sMJ9PQl-I1ax--KUY4IEgXw6h6Q4rcZ8qRGnw0Mgw4Q56xw12HBJbv76z_StsWUdLKTRfryH-k2zimUqRYV55xyits_qrUuvfrgYinR7KHqiiFcFELsWc0Z1RoClH5iAOfL9Yl-eUZfloXRm7MGdDCYFHNO4I7jw0jt06v28VT7eKpDeovlxd9jPxp-x5X-ApIl5sQ</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1655535316</pqid></control><display><type>article</type><title>Plasmapheresis in neurological disorders: Experience from a tertiary care hospital in South India</title><source>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</source><source>Medknow Open Access Medical Journals</source><source>PubMed</source><creator>Gafoor, V Abdul ; Jose, James ; Saifudheen, K ; Musthafa, Mohamed</creator><creatorcontrib>Gafoor, V Abdul ; Jose, James ; Saifudheen, K ; Musthafa, Mohamed</creatorcontrib><description>Therapeutic plasma exchange (PE) or plasmapheresis is the treatment of choice in many neurological disorders. Even though it is safe in experienced hands, there is a major concern about its safety among physicians. To analyze our experience with 230 patients who underwent PE for various neurological disorders. Retrospective review of PE procedures done during a period of 48 months, from July 2007 to June 2011 in a tertiary care teaching hospital in South India. Indications, clinical results and technical factors are discussed. The main indication for PE was GBS (203 patients; 88.3%). Age of patients ranged from 14-65 (mean = 42.3 years). The most common complications were paraesthesias and/or cramps (36.1%) and hypotension (32.2%). Four pregnant patients who underwent PE had good recovery with one intrauterine death. There was no mortality. The analysis of 240 cases of PE done in our department shows that the procedure is safe, with only minimal procedure related complications and no mortality.</description><identifier>ISSN: 0972-2327</identifier><identifier>EISSN: 1998-3549</identifier><identifier>DOI: 10.4103/0972-2327.144301</identifier><identifier>PMID: 25745304</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. Ltd</publisher><subject>Care and treatment ; Continuous flow method ; Guillain-Barré syndrome ; Methods ; Nervous system diseases ; Neurological disorders ; Original ; Plasmapheresis ; therapeutic plasma exchange</subject><ispartof>Annals of the Indian Academy of Neurology, 2015-01, Vol.18 (1), p.15-19</ispartof><rights>COPYRIGHT 2015 Medknow Publications and Media Pvt. Ltd.</rights><rights>Copyright Medknow Publications &amp; Media Pvt Ltd Jan-Mar 2015</rights><rights>Copyright: © Annals of Indian Academy of Neurology 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c628t-f93e42b193f47ff477dc8099f1e2363cb72b445a629d55d0339630481c73439e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350207/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1655535316?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25745304$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gafoor, V Abdul</creatorcontrib><creatorcontrib>Jose, James</creatorcontrib><creatorcontrib>Saifudheen, K</creatorcontrib><creatorcontrib>Musthafa, Mohamed</creatorcontrib><title>Plasmapheresis in neurological disorders: Experience from a tertiary care hospital in South India</title><title>Annals of the Indian Academy of Neurology</title><addtitle>Ann Indian Acad Neurol</addtitle><description>Therapeutic plasma exchange (PE) or plasmapheresis is the treatment of choice in many neurological disorders. Even though it is safe in experienced hands, there is a major concern about its safety among physicians. To analyze our experience with 230 patients who underwent PE for various neurological disorders. Retrospective review of PE procedures done during a period of 48 months, from July 2007 to June 2011 in a tertiary care teaching hospital in South India. Indications, clinical results and technical factors are discussed. The main indication for PE was GBS (203 patients; 88.3%). Age of patients ranged from 14-65 (mean = 42.3 years). The most common complications were paraesthesias and/or cramps (36.1%) and hypotension (32.2%). Four pregnant patients who underwent PE had good recovery with one intrauterine death. There was no mortality. The analysis of 240 cases of PE done in our department shows that the procedure is safe, with only minimal procedure related complications and no mortality.</description><subject>Care and treatment</subject><subject>Continuous flow method</subject><subject>Guillain-Barré syndrome</subject><subject>Methods</subject><subject>Nervous system diseases</subject><subject>Neurological disorders</subject><subject>Original</subject><subject>Plasmapheresis</subject><subject>therapeutic plasma exchange</subject><issn>0972-2327</issn><issn>1998-3549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqFkt2LEzEUxQdR3Lr67pMM-OLL1HxOJj4Iy7JqYUFBfQ6Z5KZNmUlqMiP635tu12qlICEEknN-ufdyquo5RkuGEX2NpCANoUQsMWMU4QfVAkvZNZQz-bBaHJ8vqic5bxHiLaPt4-qCcME4RWxR6U-DzqPebSBB9rn2oQ4wpzjEtTd6qK3PMVlI-U1982MHyUMwULsUx1rXE6TJ6_SzNjpBvYl556fiKYzPcZ429SpYr59Wj5weMjy7Py-rr-9uvlx_aG4_vl9dX902piXd1DhJgZEeS-qYcGULazokpcNAaEtNL0jPGNctkZZziyiVbemgw0ZQRiXQy2p14Nqot2qX_FgqU1F7dXcR01rpUq4ZQBkg2HJLCeoxo872WPSlCkxaJxCWpLDeHli7uR_BGghT0sMJ9PQl-I1ax--KUY4IEgXw6h6Q4rcZ8qRGnw0Mgw4Q56xw12HBJbv76z_StsWUdLKTRfryH-k2zimUqRYV55xyits_qrUuvfrgYinR7KHqiiFcFELsWc0Z1RoClH5iAOfL9Yl-eUZfloXRm7MGdDCYFHNO4I7jw0jt06v28VT7eKpDeovlxd9jPxp-x5X-ApIl5sQ</recordid><startdate>20150101</startdate><enddate>20150101</enddate><creator>Gafoor, V Abdul</creator><creator>Jose, James</creator><creator>Saifudheen, K</creator><creator>Musthafa, Mohamed</creator><general>Medknow Publications and Media Pvt. Ltd</general><general>Medknow Publications &amp; Media Pvt. Ltd</general><general>Medknow Publications &amp; Media Pvt Ltd</general><general>Wolters Kluwer Medknow Publications</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20150101</creationdate><title>Plasmapheresis in neurological disorders: Experience from a tertiary care hospital in South India</title><author>Gafoor, V Abdul ; Jose, James ; Saifudheen, K ; Musthafa, Mohamed</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c628t-f93e42b193f47ff477dc8099f1e2363cb72b445a629d55d0339630481c73439e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Care and treatment</topic><topic>Continuous flow method</topic><topic>Guillain-Barré syndrome</topic><topic>Methods</topic><topic>Nervous system diseases</topic><topic>Neurological disorders</topic><topic>Original</topic><topic>Plasmapheresis</topic><topic>therapeutic plasma exchange</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gafoor, V Abdul</creatorcontrib><creatorcontrib>Jose, James</creatorcontrib><creatorcontrib>Saifudheen, K</creatorcontrib><creatorcontrib>Musthafa, Mohamed</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>ProQuest Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Annals of the Indian Academy of Neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gafoor, V Abdul</au><au>Jose, James</au><au>Saifudheen, K</au><au>Musthafa, Mohamed</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Plasmapheresis in neurological disorders: Experience from a tertiary care hospital in South India</atitle><jtitle>Annals of the Indian Academy of Neurology</jtitle><addtitle>Ann Indian Acad Neurol</addtitle><date>2015-01-01</date><risdate>2015</risdate><volume>18</volume><issue>1</issue><spage>15</spage><epage>19</epage><pages>15-19</pages><issn>0972-2327</issn><eissn>1998-3549</eissn><abstract>Therapeutic plasma exchange (PE) or plasmapheresis is the treatment of choice in many neurological disorders. Even though it is safe in experienced hands, there is a major concern about its safety among physicians. To analyze our experience with 230 patients who underwent PE for various neurological disorders. Retrospective review of PE procedures done during a period of 48 months, from July 2007 to June 2011 in a tertiary care teaching hospital in South India. Indications, clinical results and technical factors are discussed. The main indication for PE was GBS (203 patients; 88.3%). Age of patients ranged from 14-65 (mean = 42.3 years). The most common complications were paraesthesias and/or cramps (36.1%) and hypotension (32.2%). Four pregnant patients who underwent PE had good recovery with one intrauterine death. There was no mortality. The analysis of 240 cases of PE done in our department shows that the procedure is safe, with only minimal procedure related complications and no mortality.</abstract><cop>India</cop><pub>Medknow Publications and Media Pvt. Ltd</pub><pmid>25745304</pmid><doi>10.4103/0972-2327.144301</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0972-2327
ispartof Annals of the Indian Academy of Neurology, 2015-01, Vol.18 (1), p.15-19
issn 0972-2327
1998-3549
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_ce21d5d320b143fdb17bc62126f70192
source Publicly Available Content Database (Proquest) (PQ_SDU_P3); Medknow Open Access Medical Journals; PubMed
subjects Care and treatment
Continuous flow method
Guillain-Barré syndrome
Methods
Nervous system diseases
Neurological disorders
Original
Plasmapheresis
therapeutic plasma exchange
title Plasmapheresis in neurological disorders: Experience from a tertiary care hospital in South India
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T20%3A13%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Plasmapheresis%20in%20neurological%20disorders:%20Experience%20from%20a%20tertiary%20care%20hospital%20in%20South%20India&rft.jtitle=Annals%20of%20the%20Indian%20Academy%20of%20Neurology&rft.au=Gafoor,%20V%20Abdul&rft.date=2015-01-01&rft.volume=18&rft.issue=1&rft.spage=15&rft.epage=19&rft.pages=15-19&rft.issn=0972-2327&rft.eissn=1998-3549&rft_id=info:doi/10.4103/0972-2327.144301&rft_dat=%3Cgale_doaj_%3EA401163779%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c628t-f93e42b193f47ff477dc8099f1e2363cb72b445a629d55d0339630481c73439e3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1655535316&rft_id=info:pmid/25745304&rft_galeid=A401163779&rfr_iscdi=true