The effect of lead exposure on IQ test scores in children under 12 years: a systematic review and meta-analysis of case-control studies

An inevitable exposure to the toxic heavy metal such as lead in our environmental can have irreversible effects on children's mental performance.In this study, 3316 children in 8 case-control studies were selected for review. The case group was exposed to a concentration of lead above 10 μg/dL,...

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Bibliographic Details
Published in:Systematic reviews 2022-05, Vol.11 (1), p.106-106, Article 106
Main Authors: Heidari, Serve, Mostafaei, Shayan, Razazian, Nazanin, Rajati, Mojgan, Saeedi, Anahita, Rajati, Fatemeh
Format: Article
Language:English
Subjects:
Age groups
Behavior
Blood tests
Brain research
Case-Control Studies
Child
Children
Childrens health
Humans
Intelligence Tests
Lead
Lead - toxicity
Lead poisoning
Medical research
Meta-analysis
Nervous system
Systematic review
Systematic Review Update
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Summary:An inevitable exposure to the toxic heavy metal such as lead in our environmental can have irreversible effects on children's mental performance.In this study, 3316 children in 8 case-control studies were selected for review. The case group was exposed to a concentration of lead above 10 μg/dL, and the control group was exposed to a concentration of less than 10 μg/dL, but the duration of exposure was different among studies, and the subgroup analysis was performed based on this variable.In the subgroup with duration of exposure less than the average of 4.5 years, the difference of IQ test score between two groups was significant (MD = -3.53) (P-value
ISSN:2046-4053
2046-4053
DOI:10.1186/s13643-022-01963-y