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A Fatal Case of "Bullous Erysipelas-like" Pseudomonas Vasculitis
Erysipelas is a generally benign superficial bacterial skin infection, and its bullous form constitutes a rare and more severe variant. We describe the first and fatal case of "bullous erysipelas-like" septic vasculitis due to Pseudomonas bacteremi. A 69-year-old Chinese man presenting wit...
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Published in: | Indian journal of dermatology 2016-01, Vol.61 (1), p.120-120 |
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creator | Yang, Sam Shiyao Chandran, Nisha Suyien Huang, Jing Xiang Tan, Kong-Bing Aw, Derrick Chen-Wee |
description | Erysipelas is a generally benign superficial bacterial skin infection, and its bullous form constitutes a rare and more severe variant. We describe the first and fatal case of "bullous erysipelas-like" septic vasculitis due to Pseudomonas bacteremi. A 69-year-old Chinese man presenting with diarrhea and septic shock initially began to rapidly develop sharply defined erythematous plaques with non-hemorrhagic bullae over his lower limbs. Culture of the aspirate from the bullae was positive for Pseudomonas aeruginosa. This was also consistent with his blood cultures showing Pseudomonas bacteremia. Histology of the skin lesion showed microthrombi and neutrophilic infiltrates in blood vessels with Gram-negative bacilli extruding from the vessel walls, characteristic of septic vasculitis. The bullous erysipelas-like lesions seen in this patient represents a rare manifestation of both septic vasculitis and Pseudomonas infection. |
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We describe the first and fatal case of "bullous erysipelas-like" septic vasculitis due to Pseudomonas bacteremi. A 69-year-old Chinese man presenting with diarrhea and septic shock initially began to rapidly develop sharply defined erythematous plaques with non-hemorrhagic bullae over his lower limbs. Culture of the aspirate from the bullae was positive for Pseudomonas aeruginosa. This was also consistent with his blood cultures showing Pseudomonas bacteremia. Histology of the skin lesion showed microthrombi and neutrophilic infiltrates in blood vessels with Gram-negative bacilli extruding from the vessel walls, characteristic of septic vasculitis. The bullous erysipelas-like lesions seen in this patient represents a rare manifestation of both septic vasculitis and Pseudomonas infection.</description><identifier>ISSN: 0019-5154</identifier><identifier>EISSN: 1998-3611</identifier><identifier>DOI: 10.4103/0019-5154.174095</identifier><identifier>PMID: 26955132</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. Ltd</publisher><subject>Bullous erysipelas ; Case studies ; Diagnosis ; E-IJD Case Report ; leukocytoclastic vasculitis ; Pseudomonas infections ; septic vasculitis ; Vasculitis</subject><ispartof>Indian journal of dermatology, 2016-01, Vol.61 (1), p.120-120</ispartof><rights>COPYRIGHT 2016 Medknow Publications and Media Pvt. 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We describe the first and fatal case of "bullous erysipelas-like" septic vasculitis due to Pseudomonas bacteremi. A 69-year-old Chinese man presenting with diarrhea and septic shock initially began to rapidly develop sharply defined erythematous plaques with non-hemorrhagic bullae over his lower limbs. Culture of the aspirate from the bullae was positive for Pseudomonas aeruginosa. This was also consistent with his blood cultures showing Pseudomonas bacteremia. Histology of the skin lesion showed microthrombi and neutrophilic infiltrates in blood vessels with Gram-negative bacilli extruding from the vessel walls, characteristic of septic vasculitis. The bullous erysipelas-like lesions seen in this patient represents a rare manifestation of both septic vasculitis and Pseudomonas infection.</description><subject>Bullous erysipelas</subject><subject>Case studies</subject><subject>Diagnosis</subject><subject>E-IJD Case Report</subject><subject>leukocytoclastic vasculitis</subject><subject>Pseudomonas infections</subject><subject>septic vasculitis</subject><subject>Vasculitis</subject><issn>0019-5154</issn><issn>1998-3611</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptksFv0zAUxiMEYt3gzglF47JLih07sX1BlGqDSZPgAFytF-e5uLhxsROk_fe4dBSKKh8sP__e5-dPX1G8oGTOKWGvCaGqamjD51RwoppHxYwqJSvWUvq4mB2uz4rzlNaEcEYlfVqc1a1qGsrqWfF2Ud7ACL5cQsIy2PLy3eR9mFJ5He-T26KHVHn3HS_LTwmnPmzCAKn8CslM3o0uPSueWPAJnz_sF8WXm-vPyw_V3cf3t8vFXWUa1YxVB1xJUpuWSsYNqTvO65oC5LPqWSvQUC4NyM6avpdWoUIrpe07Yi3YvmYXxe1etw-w1tvoNhDvdQCnfxdCXGmIozMetUGhWtu2tEPFbcNk34G1TAgwNg9BstabvdZ26jbYGxzGCP5I9PhmcN_0KvzUXLSs5SwLXD0IxPBjwjTqjUsGvYcBs3eaClFTLjgVGX31H7oOUxyyVZlqiWRScvmXWkH-gBtsyO-anahecE55o2pBM1WdoFY4YB4yDGhdLh_x8xN8Xj1unDnZQPYNJoaUItqDJ5ToXeL0LlJ6Fym9T1xuefmvl4eGPxFjvwAUHM5K</recordid><startdate>201601</startdate><enddate>201601</enddate><creator>Yang, Sam Shiyao</creator><creator>Chandran, Nisha Suyien</creator><creator>Huang, Jing Xiang</creator><creator>Tan, Kong-Bing</creator><creator>Aw, Derrick Chen-Wee</creator><general>Medknow Publications and Media Pvt. 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subjects | Bullous erysipelas Case studies Diagnosis E-IJD Case Report leukocytoclastic vasculitis Pseudomonas infections septic vasculitis Vasculitis |
title | A Fatal Case of "Bullous Erysipelas-like" Pseudomonas Vasculitis |
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