Enhancing resistance to Salmonella typhimurium in yellow-feathered broilers: a study of a strain of Lactiplantibacillus plantarum as probiotic feed additives

• Published in: Frontiers in microbiology 2024-11, Vol.15, p.1450690
• Main Authors: Yin, Yangyan, Peng, Hao, Bai, Huili, Pei, Zhe, Chen, Zhongwei, Ma, Chunxia, Zhu, Min, Li, Jun, Li, Changting, Gong, Yu, Wang, Leping, Teng, Ling, Qin, Zhongsheng, Zhou, Jianhui, Wei, Tianchao, Liao, Yuying
• Format: Article
• Language: English
• Subjects: growth performance; gut health; immune response; intestine tissue; Microbiology; probiotics; yellow-feathered broiler
• ISSN: 1664-302X; 1664-302X
• DOI: 10.3389/fmicb.2024.1450690

strains are potentially rich sources of probiotics that could help avoid infections. In order to evaluate their efficacy in bolstering resistance to infection among chicks. In this study, and commercial probiotics were administered via the water supply at a dosage of 1×10 CFU per chicken from days 1 to 7 to establish a protective system for the chicks. On days 8 and 9, was attacked to investigate the preventive effects and potential mechanisms of in comparison with commercial probiotics. Post-treatment, we took a broad range of measurements, including body weight, immune organ index changes, the viable count of in the liver, spleen, and cecum, as well as pathological changes in the liver. Our findings demonstrated that both and the commercial probiotic could safeguard chicks from infection. The data also suggested that probiotic medication could ease weight loss postinfection, lower the bacterial count in the liver, spleen, and cecum, and attenuate liver pathological damage among all treated participants. Subsequently, we did high-throughput sequencing of 16S rRNA to examine the fecal microbiota of the chicks 5  days post-infection. We discovered that both and the commercial probiotic could fend off the invasion of by affecting the bacterial population of , and . Generally speaking, the addition of as a feed additive protects yellow-feathered broilers from illness, suggesting great potential for commercial uses in the poultry industry.