Corticobasal Syndrome Associated with Antiphospholipid Syndrome Secondary to Systemic Lupus Erythematosus

We report the case of a 53-year-old woman diagnosed with corticobasal syndrome (CBS) due to antiphospholipid syndrome (APS) secondary to systemic lupus erythematosus. Brain MRI showed marked cortical atrophy, several small infarctions in the deep white matter, and mild white matter changes, all of w...

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Bibliographic Details
Published in:Case reports in neurological medicine 2018-01, Vol.2018 (2018), p.1-4
Main Authors: Kato, Hiroyuki, Tagawa, Asako, Ogawa, Tomoko, Hashimoto, R.
Format: Article
Language:English
Subjects:
Antiphospholipid syndrome
Autoimmune diseases
Blood clot
Case Report
Case reports
Dabigatran etexilate
Dementia
Deoxyribonucleic acid
DNA
Health aspects
Immunoglobulins
Laboratories
Lupus
Nervous system diseases
Neurology
Patients
Rheumatology
Systemic lupus erythematosus
Thrombosis
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Summary:We report the case of a 53-year-old woman diagnosed with corticobasal syndrome (CBS) due to antiphospholipid syndrome (APS) secondary to systemic lupus erythematosus. Brain MRI showed marked cortical atrophy, several small infarctions in the deep white matter, and mild white matter changes, all of which were probably due to thrombosis manifestations of APS and could also be related to the CBS. To the best of our knowledge, this is the fourth reported case of CBS due to APS. It is noteworthy that although the common underlying pathologies of the CBS are neurodegenerative diseases, either primary or secondary APS can manifest itself as the CBS.
ISSN:2090-6668
2090-6676
DOI:10.1155/2018/5872638