A review of the application of cellulose hemostatic agent on trauma injuries

Planning for management of bleeding in trauma injuries is very important. The initial purpose in emergency situations should be immediate establishment of an efficient hemostasis, principally in its topical application. In this study, we aimed to review the major relevant articles in the case of app...

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Bibliographic Details
Published in:Open access emergency medicine 2019-08, Vol.11, p.171-177
Main Authors: Khoshmohabat, Hadi, Paydar, Shahram, Makarem, Alireza, Karami, Mohammad Yasin, Dastgheib, Niloofar, Zahraei, Seyed Ali Hossein, Rezaei, Rohallah, Mahmoudi Nezhad, Golnoush Sadat
Format: Article
Language:English
Subjects:
Abdomen
Adhesives
Albinism
Cellulose
Cellulose hemostatic agent
Collagen
Diabetes
Hemorrhage
Injuries
injury
Liver
Mortality
Online databases
Ostomy
Polysaccharides
Review
Studies
Surgery
Systematic review
Trauma
Zeolites
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Summary:Planning for management of bleeding in trauma injuries is very important. The initial purpose in emergency situations should be immediate establishment of an efficient hemostasis, principally in its topical application. In this study, we aimed to review the major relevant articles in the case of application of cellulose hemostatic agent on trauma injuries. We searched the online databases such as PubMed, MEDLINE, Wiley, EMBASE, ISI Web of Knowledge, and Scopus. Two reviewers independently searched and assessed the titles and abstracts of all articles. Upon screening the titles and abstracts, 24 studies were identified for full-text review. The oxidized cellulose had the best clotting times, while it demonstrated low absorption ability. Surgical and thermosensitive chitosan hemostatic could be valuable for managing hemorrhage from liver injuries in trauma patients. Recently, the application of cellulose hemostatic agents has been one of the main improvements obtained for controlling bleeding in trauma injuries. However, generally according to the literature review, the decision about using each agent should be made on a case-by-case basis. However, it can be mentioned that the perfect hemostatic agent has not been still identified.
ISSN:1179-1500
1179-1500
DOI:10.2147/OAEM.S205006