Identification and Evaluations of Novel Insecticidal Proteins from Plants of the Class Polypodiopsida for Crop Protection against Key Lepidopteran Pests

Various lepidopteran insects are responsible for major crop losses worldwide. Although crop plant varieties developed to express (Bt) proteins are effective at controlling damage from key lepidopteran pests, some insect populations have evolved to be insensitive to certain Bt proteins. Here, we repo...

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Published in:Toxins 2019-07, Vol.11 (7), p.383
Main Authors: Liu, Lu, Schepers, Eric, Lum, Amy, Rice, Janet, Yalpani, Nasser, Gerber, Ryan, Jiménez-Juárez, Nuria, Haile, Fikru, Pascual, Alejandra, Barry, Jennifer, Qi, Xiuli, Kassa, Adane, Heckert, Matthew J, Xie, Weiping, Ding, Changkui, Oral, Jarred, Nguyen, Minh, Le, James, Procyk, Lisa, Diehn, Scott H, Crane, Virginia C, Damude, Howard, Pilcher, Carol, Booth, Russ, Zhu, Genhai, Nowatzki, Timothy M, Nelson, Mark E, Lu, Albert L, Wu, Gusui
Format: Article
Language:English
Subjects:
Adiantum - genetics
Animals
Chromatography
Comparative studies
Cotton
Crop Protection
Crops
Damage
Flowers & plants
genetically modified
Glycine max - genetics
Homology
Insect control
insecticidal
Insecticide resistance
Insecticides
Insects
lepidopteran
Moths
Pest Control, Biological
Pests
Plant protection
plant protein
Plant Proteins - genetics
Plants, Genetically Modified
Proteins
Recombinant Proteins - toxicity
resistance management
Soybeans
Transgenic plants
Zea mays - genetics
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cited_by cdi_FETCH-LOGICAL-c484t-7c1910b524569265db3d498f43a88956d7e37c4a651ff0907b13339c4b67791e3
cites cdi_FETCH-LOGICAL-c484t-7c1910b524569265db3d498f43a88956d7e37c4a651ff0907b13339c4b67791e3
container_end_page
container_issue 7
container_start_page 383
container_title Toxins
container_volume 11
creator Liu, Lu
Schepers, Eric
Lum, Amy
Rice, Janet
Yalpani, Nasser
Gerber, Ryan
Jiménez-Juárez, Nuria
Haile, Fikru
Pascual, Alejandra
Barry, Jennifer
Qi, Xiuli
Kassa, Adane
Heckert, Matthew J
Xie, Weiping
Ding, Changkui
Oral, Jarred
Nguyen, Minh
Le, James
Procyk, Lisa
Diehn, Scott H
Crane, Virginia C
Damude, Howard
Pilcher, Carol
Booth, Russ
Liu, Lu
Zhu, Genhai
Nowatzki, Timothy M
Nelson, Mark E
Lu, Albert L
Wu, Gusui
description Various lepidopteran insects are responsible for major crop losses worldwide. Although crop plant varieties developed to express (Bt) proteins are effective at controlling damage from key lepidopteran pests, some insect populations have evolved to be insensitive to certain Bt proteins. Here, we report the discovery of a family of homologous proteins, two of which we have designated IPD083Aa and IPD083Cb, which are from . Both proteins share no known peptide domains, sequence motifs, or signatures with other proteins. Transgenic soybean or corn plants expressing either IPD083Aa or IPD083Cb, respectively, show protection from feeding damage by several key pests under field conditions. The results from comparative studies with major Bt proteins currently deployed in transgenic crops indicate that the IPD083 proteins function by binding to different target sites. These results indicate that IPD083Aa and IPD083Cb can serve as alternatives to traditional Bt-based insect control traits with potential to counter insect resistance to Bt proteins.
doi_str_mv 10.3390/toxins11070383
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subjects Adiantum - genetics
Animals
Chromatography
Comparative studies
Cotton
Crop Protection
Crops
Damage
Flowers & plants
genetically modified
Glycine max - genetics
Homology
Insect control
insecticidal
Insecticide resistance
Insecticides
Insects
lepidopteran
Moths
Pest Control, Biological
Pests
Plant protection
plant protein
Plant Proteins - genetics
Plants, Genetically Modified
Proteins
Recombinant Proteins - toxicity
resistance management
Soybeans
Transgenic plants
Zea mays - genetics
title Identification and Evaluations of Novel Insecticidal Proteins from Plants of the Class Polypodiopsida for Crop Protection against Key Lepidopteran Pests
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T20%3A54%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Identification%20and%20Evaluations%20of%20Novel%20Insecticidal%20Proteins%20from%20Plants%20of%20the%20Class%20Polypodiopsida%20for%20Crop%20Protection%20against%20Key%20Lepidopteran%20Pests&rft.jtitle=Toxins&rft.au=Liu,%20Lu&rft.date=2019-07-01&rft.volume=11&rft.issue=7&rft.spage=383&rft.pages=383-&rft.issn=2072-6651&rft.eissn=2072-6651&rft_id=info:doi/10.3390/toxins11070383&rft_dat=%3Cproquest_doaj_%3E2550280426%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c484t-7c1910b524569265db3d498f43a88956d7e37c4a651ff0907b13339c4b67791e3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2550280426&rft_id=info:pmid/31266212&rfr_iscdi=true