Tuberculosis and latent tuberculosis in prison inmates

• Published in: Revista de saúde pública 2012-02, Vol.46 (1), p.119-127
• Main Authors: Nogueira, Péricles Alves, Abrahão, Regina Maura Cabral de Melo, Galesi, Vera Maria Neder
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Brazil - epidemiology; Epidemiologic Methods; Epidemiología; Female; Health Policy & Services; Humans; Latent Tuberculosis - diagnosis; Latent Tuberculosis - epidemiology; Latent Tuberculosis - microbiology; Male; Middle Aged; Mycobacterium tuberculosis; Mycobacterium tuberculosis - isolation & purification; Prisioneros; Prisoners - statistics & numerical data; Prisons - statistics & numerical data; Prueba de tuberculina; Pruebas de sensibilidad microbiana; Socioeconomic Factors; Sputum - microbiology; Tuberculin Test; Tuberculosis Latente; Tuberculosis, Pulmonary - diagnosis; Tuberculosis, Pulmonary - epidemiology; Tuberculosis, Pulmonary - microbiology; Young Adult
• ISSN: 0034-8910; 1518-8787; 1518-8787; 0034-8910
• DOI: 10.1590/S0034-89102011005000080

To estimate the prevalences of tuberculosis and latent tuberculosis in inmates. Observational study was carried out with inmates of a prison and a jail in the State of São Paulo, Southeastern Brazil, between March and December of 2008. Questionnaires were used to collect sociodemographic and epidemiological data. Tuberculin skin testing was administered (PPD-RT23-2TU/0.1 mL), and the following laboratory tests were also performed: sputum smear examination, sputum culture, identification of strains isolated and drug susceptibility testing. The variables were compared using Pearson's chi-square (Χ2) association test, Fisher's exact test and the proportion test. Of the 2,435 inmates interviewed, 2,237 (91.9%) agreed to submit to tuberculin skin testing and of these, 73.0% had positive reactions. The prevalence of tuberculosis was 830.6 per 100,000 inmates. The coefficients of prevalence were 1,029.5/100,000 for inmates of the prison and 525.7/100,000 for inmates of the jail. The sociodemographic characteristics of the inmates in the two groups studied were similar; most of the inmates were young and single with little schooling. The epidemiological characteristics differed between the prison units, with the number of cases of previous tuberculosis and of previous contact with the disease greater in the prison and coughing, expectoration and smoking more common in the jail. Among the 20 Mycobacterium tuberculosis strains identified, 95.0% were sensitive to anti-tuberculosis drugs, and 5.0% were resistant to streptomycin. The prevalences of tuberculosis and latent tuberculosis were higher in the incarcerated population than in the general population, and they were also higher in the prison than in the jail.