Orchestrating the fecal microbiota transplantation: Current technological advancements and potential biomedical application

Fecal microbiota transplantation (FMT) has been proved to be an effective treatment for gastrointestinal disorders caused due to microbial disbalance. Nowadays, this approach is being used to treat extragastrointestinal conditions like metabolic and neurological disorders, which are considered to ha...

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Bibliographic Details
Published in:Frontiers in medical technology 2022-09, Vol.4, p.961569-961569
Main Authors: Nigam, Manisha, Panwar, Abhaya Shikhar, Singh, Rahul Kunwar
Format: Article
Language:English
Subjects:
dysbiosis
extragastrointestinal
gastrointestinal
gut microbiota
Medical Technology
microbiome
safety
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Summary:Fecal microbiota transplantation (FMT) has been proved to be an effective treatment for gastrointestinal disorders caused due to microbial disbalance. Nowadays, this approach is being used to treat extragastrointestinal conditions like metabolic and neurological disorders, which are considered to have their provenance in microbial dysbiosis in the intestine. Even though case studies and clinical trials have demonstrated the potential of FMT in treating a variety of ailments, safety and ethical concerns must be answered before the technique is widely used to the community's overall benefit. From this perspective, it is not unexpected that techniques for altering gut microbiota may represent a form of medication whose potential has not yet been thoroughly addressed. This review intends to gather data on recent developments in FMT and its safety, constraints, and ethical considerations.
ISSN:2673-3129
2673-3129
DOI:10.3389/fmedt.2022.961569