Loading…
The effect of prostate tissue inflammation in benign prostatic hyperplasia on enhancer of zeste homolog 2 ribonucleic acid expression
Enhancer of zeste homolog 2 (EZH2) has been recently found to regulate several genes involved in immunoresponse and autocrine inflammation network. The aim of the study was to quantitate EZH2 messenger ribonucleic acid (mRNA) expression, evaluate its relation to conditions of prostatitis associated...
Saved in:
| Published in: | Annals of Saudi medicine 2012-05, Vol.32 (3), p.262-268 |
|---|---|
| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c563t-580d67824e174adf82d499e8aa8e6130ba59cd2385e7ced9c5572494eca87afe3 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c563t-580d67824e174adf82d499e8aa8e6130ba59cd2385e7ced9c5572494eca87afe3 |
| container_end_page | 268 |
| container_issue | 3 |
| container_start_page | 262 |
| container_title | Annals of Saudi medicine |
| container_volume | 32 |
| creator | Al-Maghrebi, May Kehinde, Elijah O Al-Mulla, Fahd Anim, Jehoram T |
| description | Enhancer of zeste homolog 2 (EZH2) has been recently found to regulate several genes involved in immunoresponse and autocrine inflammation network. The aim of the study was to quantitate EZH2 messenger ribonucleic acid (mRNA) expression, evaluate its relation to conditions of prostatitis associated with benign prostatic hyperplasia (BPH), and correlate it with the levels of the inflammatory marker interlukin 6 (IL-6).
Cross-sectional study in Middle Eastern men with BPH and prostatitis or BPH only.
Transrectal ultrasound-guided prostate biopsies were collected from 106 patients suspected of having prostate cancer; however, the histology revealed BPH. Upon further pathological examination, 56 of these cases were identified as BPH with prostatitis and classified as: acute prostatitis (n=13); active chronic prostatitis (n=32); and, chronic inactive prostatitis (n=12). Serum IL-6 levels and EZH2 mRNA expression were measured and compared between patient groups.
EZH2 mRNA was overexpressed in BPH with prostatitis patients compared to BPH only patients (P |
| doi_str_mv | 10.5144/0256-4947.2012.262 |
| format | article |
| fullrecord | <record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_d02d136b1a6549f2856808c63fafce53</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A317588840</galeid><doaj_id>oai_doaj_org_article_d02d136b1a6549f2856808c63fafce53</doaj_id><sourcerecordid>A317588840</sourcerecordid><originalsourceid>FETCH-LOGICAL-c563t-580d67824e174adf82d499e8aa8e6130ba59cd2385e7ced9c5572494eca87afe3</originalsourceid><addsrcrecordid>eNptkktv1DAUhSMEoqXwB1igSGzYzOB3nA1SVfGoVIlNWVt3nOsZjxI72Alq2fO_cTqdQhHKwrF9zmfde09VvaZkLakQ7wmTaiVa0awZoWzNFHtSnZK2kSshlHpa_o-Ck-pFzntCGBGcP69OGJNaC96cVr-ud1ijc2inOrp6TDFPMGE9-ZxnrH1wPQwDTD6Gsqk3GPw2HGXe1rvbEdPYQ_ZQFwmGHQSLaWH9xFxAuzjEPm5rVie_iWG2PRYbWN_VeDMmzLmgX1bPHPQZX92vZ9W3Tx-vL76srr5-vrw4v1pZqfi0kpp0qtFMIG0EdE6zTrQtagCNinKyAdnajnEtsbHYtVbKhpX60YJuwCE_qy4P3C7C3ozJD5BuTQRv7g5i2hpIpaweTUdYR7naUFBStI5pqTTRVnEHzqLkhfXhwBrnzYCdxTAl6B9BH98EvzPb-MMooikRpADe3QNS_D6XZpnBZ4t9DwHjnA0lVFDKhWyK9O0_0n2cUyitMowzzaVuuPij2kIpoIwulnftAjXnnDZl5Pru2fV_VOXrcPA2BnS-nD8ysIPBlqnnhO6hRkrMEkSz5MwsOTNLEE0JYjG9-bs7D5Zj8vhvPsnZug</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2328358734</pqid></control><display><type>article</type><title>The effect of prostate tissue inflammation in benign prostatic hyperplasia on enhancer of zeste homolog 2 ribonucleic acid expression</title><source>PubMed Central</source><creator>Al-Maghrebi, May ; Kehinde, Elijah O ; Al-Mulla, Fahd ; Anim, Jehoram T</creator><creatorcontrib>Al-Maghrebi, May ; Kehinde, Elijah O ; Al-Mulla, Fahd ; Anim, Jehoram T</creatorcontrib><description>Enhancer of zeste homolog 2 (EZH2) has been recently found to regulate several genes involved in immunoresponse and autocrine inflammation network. The aim of the study was to quantitate EZH2 messenger ribonucleic acid (mRNA) expression, evaluate its relation to conditions of prostatitis associated with benign prostatic hyperplasia (BPH), and correlate it with the levels of the inflammatory marker interlukin 6 (IL-6).
Cross-sectional study in Middle Eastern men with BPH and prostatitis or BPH only.
Transrectal ultrasound-guided prostate biopsies were collected from 106 patients suspected of having prostate cancer; however, the histology revealed BPH. Upon further pathological examination, 56 of these cases were identified as BPH with prostatitis and classified as: acute prostatitis (n=13); active chronic prostatitis (n=32); and, chronic inactive prostatitis (n=12). Serum IL-6 levels and EZH2 mRNA expression were measured and compared between patient groups.
EZH2 mRNA was overexpressed in BPH with prostatitis patients compared to BPH only patients (P<.0001). BPH with active chronic prostatitis had higher EZH2 expression than BPH with acute or chronic inactive prostatitis compared to BPH only (P=.05 and .73, respectively). EZH2 mRNA expression showed a negative correlation with IL-6 concentrations in BPH with prostatitis patients (rs=-0.31, P=.02). EZH2 overexpression was associated with an increased risk of having BPH with prostatitis (crude odds ratio 0.20, 95% CI 0.06-0.65, P=.0076).
EZH2 mRNA expression correlates positively with prostatitis conditions associated with BPH and negatively with serum IL-6 levels. This supports the possible involvement of EZH2 mRNA overexpression in the development of prostate inflammation, and its new regulatory role in suppressing the expression of some inflammatory network genes.</description><identifier>ISSN: 0256-4947</identifier><identifier>EISSN: 0975-4466</identifier><identifier>DOI: 10.5144/0256-4947.2012.262</identifier><identifier>PMID: 22588437</identifier><language>eng</language><publisher>Saudi Arabia: Medknow Publications and Media Pvt. Ltd</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Antigens ; Biomarkers ; Biopsy ; Cross-Sectional Studies ; Deoxyribonucleic acid ; DNA ; DNA-Binding Proteins - genetics ; DNA-Binding Proteins - metabolism ; Enhancer of Zeste Homolog 2 Protein ; Gene expression ; Genital diseases ; Histology ; Humans ; Hyperplasia ; Inflammation ; Interleukin-6 - blood ; Male ; Middle Aged ; Original ; Pathogenesis ; Patients ; Polycomb Repressive Complex 2 ; Polymerase chain reaction ; Prostate - pathology ; Prostate cancer ; Prostate-Specific Antigen - blood ; Prostatic Hyperplasia - complications ; Prostatic Hyperplasia - metabolism ; Prostatic Hyperplasia - pathology ; Prostatitis - complications ; Prostatitis - metabolism ; Prostatitis - pathology ; RNA, Messenger - analysis ; Transcription Factors - genetics ; Transcription Factors - metabolism</subject><ispartof>Annals of Saudi medicine, 2012-05, Vol.32 (3), p.262-268</ispartof><rights>COPYRIGHT 2012 Medknow Publications and Media Pvt. Ltd.</rights><rights>2012. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2012, Annals of Saudi Medicine 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c563t-580d67824e174adf82d499e8aa8e6130ba59cd2385e7ced9c5572494eca87afe3</citedby><cites>FETCH-LOGICAL-c563t-580d67824e174adf82d499e8aa8e6130ba59cd2385e7ced9c5572494eca87afe3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081040/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081040/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22588437$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Al-Maghrebi, May</creatorcontrib><creatorcontrib>Kehinde, Elijah O</creatorcontrib><creatorcontrib>Al-Mulla, Fahd</creatorcontrib><creatorcontrib>Anim, Jehoram T</creatorcontrib><title>The effect of prostate tissue inflammation in benign prostatic hyperplasia on enhancer of zeste homolog 2 ribonucleic acid expression</title><title>Annals of Saudi medicine</title><addtitle>Ann Saudi Med</addtitle><description>Enhancer of zeste homolog 2 (EZH2) has been recently found to regulate several genes involved in immunoresponse and autocrine inflammation network. The aim of the study was to quantitate EZH2 messenger ribonucleic acid (mRNA) expression, evaluate its relation to conditions of prostatitis associated with benign prostatic hyperplasia (BPH), and correlate it with the levels of the inflammatory marker interlukin 6 (IL-6).
Cross-sectional study in Middle Eastern men with BPH and prostatitis or BPH only.
Transrectal ultrasound-guided prostate biopsies were collected from 106 patients suspected of having prostate cancer; however, the histology revealed BPH. Upon further pathological examination, 56 of these cases were identified as BPH with prostatitis and classified as: acute prostatitis (n=13); active chronic prostatitis (n=32); and, chronic inactive prostatitis (n=12). Serum IL-6 levels and EZH2 mRNA expression were measured and compared between patient groups.
EZH2 mRNA was overexpressed in BPH with prostatitis patients compared to BPH only patients (P<.0001). BPH with active chronic prostatitis had higher EZH2 expression than BPH with acute or chronic inactive prostatitis compared to BPH only (P=.05 and .73, respectively). EZH2 mRNA expression showed a negative correlation with IL-6 concentrations in BPH with prostatitis patients (rs=-0.31, P=.02). EZH2 overexpression was associated with an increased risk of having BPH with prostatitis (crude odds ratio 0.20, 95% CI 0.06-0.65, P=.0076).
EZH2 mRNA expression correlates positively with prostatitis conditions associated with BPH and negatively with serum IL-6 levels. This supports the possible involvement of EZH2 mRNA overexpression in the development of prostate inflammation, and its new regulatory role in suppressing the expression of some inflammatory network genes.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Antigens</subject><subject>Biomarkers</subject><subject>Biopsy</subject><subject>Cross-Sectional Studies</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>DNA-Binding Proteins - genetics</subject><subject>DNA-Binding Proteins - metabolism</subject><subject>Enhancer of Zeste Homolog 2 Protein</subject><subject>Gene expression</subject><subject>Genital diseases</subject><subject>Histology</subject><subject>Humans</subject><subject>Hyperplasia</subject><subject>Inflammation</subject><subject>Interleukin-6 - blood</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Original</subject><subject>Pathogenesis</subject><subject>Patients</subject><subject>Polycomb Repressive Complex 2</subject><subject>Polymerase chain reaction</subject><subject>Prostate - pathology</subject><subject>Prostate cancer</subject><subject>Prostate-Specific Antigen - blood</subject><subject>Prostatic Hyperplasia - complications</subject><subject>Prostatic Hyperplasia - metabolism</subject><subject>Prostatic Hyperplasia - pathology</subject><subject>Prostatitis - complications</subject><subject>Prostatitis - metabolism</subject><subject>Prostatitis - pathology</subject><subject>RNA, Messenger - analysis</subject><subject>Transcription Factors - genetics</subject><subject>Transcription Factors - metabolism</subject><issn>0256-4947</issn><issn>0975-4466</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNptkktv1DAUhSMEoqXwB1igSGzYzOB3nA1SVfGoVIlNWVt3nOsZjxI72Alq2fO_cTqdQhHKwrF9zmfde09VvaZkLakQ7wmTaiVa0awZoWzNFHtSnZK2kSshlHpa_o-Ck-pFzntCGBGcP69OGJNaC96cVr-ud1ijc2inOrp6TDFPMGE9-ZxnrH1wPQwDTD6Gsqk3GPw2HGXe1rvbEdPYQ_ZQFwmGHQSLaWH9xFxAuzjEPm5rVie_iWG2PRYbWN_VeDMmzLmgX1bPHPQZX92vZ9W3Tx-vL76srr5-vrw4v1pZqfi0kpp0qtFMIG0EdE6zTrQtagCNinKyAdnajnEtsbHYtVbKhpX60YJuwCE_qy4P3C7C3ozJD5BuTQRv7g5i2hpIpaweTUdYR7naUFBStI5pqTTRVnEHzqLkhfXhwBrnzYCdxTAl6B9BH98EvzPb-MMooikRpADe3QNS_D6XZpnBZ4t9DwHjnA0lVFDKhWyK9O0_0n2cUyitMowzzaVuuPij2kIpoIwulnftAjXnnDZl5Pru2fV_VOXrcPA2BnS-nD8ysIPBlqnnhO6hRkrMEkSz5MwsOTNLEE0JYjG9-bs7D5Zj8vhvPsnZug</recordid><startdate>20120501</startdate><enddate>20120501</enddate><creator>Al-Maghrebi, May</creator><creator>Kehinde, Elijah O</creator><creator>Al-Mulla, Fahd</creator><creator>Anim, Jehoram T</creator><general>Medknow Publications and Media Pvt. Ltd</general><general>KING FAISAL SPECIALIST HOSPITAL & RESEARCH CENTRE</general><general>King Faisal Specialist Hospital and Research Centre</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>CWDGH</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20120501</creationdate><title>The effect of prostate tissue inflammation in benign prostatic hyperplasia on enhancer of zeste homolog 2 ribonucleic acid expression</title><author>Al-Maghrebi, May ; Kehinde, Elijah O ; Al-Mulla, Fahd ; Anim, Jehoram T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c563t-580d67824e174adf82d499e8aa8e6130ba59cd2385e7ced9c5572494eca87afe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Antigens</topic><topic>Biomarkers</topic><topic>Biopsy</topic><topic>Cross-Sectional Studies</topic><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>DNA-Binding Proteins - genetics</topic><topic>DNA-Binding Proteins - metabolism</topic><topic>Enhancer of Zeste Homolog 2 Protein</topic><topic>Gene expression</topic><topic>Genital diseases</topic><topic>Histology</topic><topic>Humans</topic><topic>Hyperplasia</topic><topic>Inflammation</topic><topic>Interleukin-6 - blood</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Original</topic><topic>Pathogenesis</topic><topic>Patients</topic><topic>Polycomb Repressive Complex 2</topic><topic>Polymerase chain reaction</topic><topic>Prostate - pathology</topic><topic>Prostate cancer</topic><topic>Prostate-Specific Antigen - blood</topic><topic>Prostatic Hyperplasia - complications</topic><topic>Prostatic Hyperplasia - metabolism</topic><topic>Prostatic Hyperplasia - pathology</topic><topic>Prostatitis - complications</topic><topic>Prostatitis - metabolism</topic><topic>Prostatitis - pathology</topic><topic>RNA, Messenger - analysis</topic><topic>Transcription Factors - genetics</topic><topic>Transcription Factors - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Al-Maghrebi, May</creatorcontrib><creatorcontrib>Kehinde, Elijah O</creatorcontrib><creatorcontrib>Al-Mulla, Fahd</creatorcontrib><creatorcontrib>Anim, Jehoram T</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Middle East & Africa Database</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Research Library</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Annals of Saudi medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Al-Maghrebi, May</au><au>Kehinde, Elijah O</au><au>Al-Mulla, Fahd</au><au>Anim, Jehoram T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of prostate tissue inflammation in benign prostatic hyperplasia on enhancer of zeste homolog 2 ribonucleic acid expression</atitle><jtitle>Annals of Saudi medicine</jtitle><addtitle>Ann Saudi Med</addtitle><date>2012-05-01</date><risdate>2012</risdate><volume>32</volume><issue>3</issue><spage>262</spage><epage>268</epage><pages>262-268</pages><issn>0256-4947</issn><eissn>0975-4466</eissn><abstract>Enhancer of zeste homolog 2 (EZH2) has been recently found to regulate several genes involved in immunoresponse and autocrine inflammation network. The aim of the study was to quantitate EZH2 messenger ribonucleic acid (mRNA) expression, evaluate its relation to conditions of prostatitis associated with benign prostatic hyperplasia (BPH), and correlate it with the levels of the inflammatory marker interlukin 6 (IL-6).
Cross-sectional study in Middle Eastern men with BPH and prostatitis or BPH only.
Transrectal ultrasound-guided prostate biopsies were collected from 106 patients suspected of having prostate cancer; however, the histology revealed BPH. Upon further pathological examination, 56 of these cases were identified as BPH with prostatitis and classified as: acute prostatitis (n=13); active chronic prostatitis (n=32); and, chronic inactive prostatitis (n=12). Serum IL-6 levels and EZH2 mRNA expression were measured and compared between patient groups.
EZH2 mRNA was overexpressed in BPH with prostatitis patients compared to BPH only patients (P<.0001). BPH with active chronic prostatitis had higher EZH2 expression than BPH with acute or chronic inactive prostatitis compared to BPH only (P=.05 and .73, respectively). EZH2 mRNA expression showed a negative correlation with IL-6 concentrations in BPH with prostatitis patients (rs=-0.31, P=.02). EZH2 overexpression was associated with an increased risk of having BPH with prostatitis (crude odds ratio 0.20, 95% CI 0.06-0.65, P=.0076).
EZH2 mRNA expression correlates positively with prostatitis conditions associated with BPH and negatively with serum IL-6 levels. This supports the possible involvement of EZH2 mRNA overexpression in the development of prostate inflammation, and its new regulatory role in suppressing the expression of some inflammatory network genes.</abstract><cop>Saudi Arabia</cop><pub>Medknow Publications and Media Pvt. Ltd</pub><pmid>22588437</pmid><doi>10.5144/0256-4947.2012.262</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0256-4947 |
| ispartof | Annals of Saudi medicine, 2012-05, Vol.32 (3), p.262-268 |
| issn | 0256-4947 0975-4466 |
| language | eng |
| recordid | cdi_doaj_primary_oai_doaj_org_article_d02d136b1a6549f2856808c63fafce53 |
| source | PubMed Central |
| subjects | Adult Aged Aged, 80 and over Antigens Biomarkers Biopsy Cross-Sectional Studies Deoxyribonucleic acid DNA DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Enhancer of Zeste Homolog 2 Protein Gene expression Genital diseases Histology Humans Hyperplasia Inflammation Interleukin-6 - blood Male Middle Aged Original Pathogenesis Patients Polycomb Repressive Complex 2 Polymerase chain reaction Prostate - pathology Prostate cancer Prostate-Specific Antigen - blood Prostatic Hyperplasia - complications Prostatic Hyperplasia - metabolism Prostatic Hyperplasia - pathology Prostatitis - complications Prostatitis - metabolism Prostatitis - pathology RNA, Messenger - analysis Transcription Factors - genetics Transcription Factors - metabolism |
| title | The effect of prostate tissue inflammation in benign prostatic hyperplasia on enhancer of zeste homolog 2 ribonucleic acid expression |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T15%3A14%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20effect%20of%20prostate%20tissue%20inflammation%20in%20benign%20prostatic%20hyperplasia%20on%20enhancer%20of%20zeste%20homolog%202%20ribonucleic%20acid%20expression&rft.jtitle=Annals%20of%20Saudi%20medicine&rft.au=Al-Maghrebi,%20May&rft.date=2012-05-01&rft.volume=32&rft.issue=3&rft.spage=262&rft.epage=268&rft.pages=262-268&rft.issn=0256-4947&rft.eissn=0975-4466&rft_id=info:doi/10.5144/0256-4947.2012.262&rft_dat=%3Cgale_doaj_%3EA317588840%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c563t-580d67824e174adf82d499e8aa8e6130ba59cd2385e7ced9c5572494eca87afe3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2328358734&rft_id=info:pmid/22588437&rft_galeid=A317588840&rfr_iscdi=true |