Cognitive frailty among Malaysian older adults: baseline findings from the LRGS TUA cohort study

• Published in: Clinical interventions in aging 2019-07, Vol.14, p.1343-1352
• Main Authors: Malek Rivan, Nurul Fatin, Shahar, Suzana, Rajab, Nor Fadilah, Singh, Devinder Kaur Ajit, Din, Normah Che, Hazlina, Mahadzir, Hamid, Tengku Aizan Tengku Abdul
• Format: Article
• Language: English
• Subjects: Activities of Daily Living; Aged; Aged, 80 and over; Aging; Analysis; Biological markers; Biomarkers; Blood pressure; Body composition; Cognition; Cognitive ability; Cognitive Dysfunction - epidemiology; cognitive frailty; Cohort analysis; Cross-Sectional Studies; Data collection; Dementia; Demography; Diet; DNA damage; Female; Frail Elderly - statistics & numerical data; Frailty; Frailty - epidemiology; Geriatrics; Gerontology; Health sciences; Humans; Independent Living; Life Style; Logistic Models; Longitudinal Studies; Malaysia - epidemiology; Male; Mental Health; Middle Aged; mild cognitive impairment; Niacin; Niacin - blood; older adults; Older people; Original Research; Oxidative stress; Oxidative Stress - physiology; Physical fitness; Physical Functional Performance; Population; Quality of life; Questionnaires; Social support; Socioeconomic Factors; Surveys; Telomerase; Telomerase - metabolism
• ISSN: 1178-1998; 1176-9092; 1178-1998
• DOI: 10.2147/cia.s211027

This study was aimed at determining the presence of cognitive frailty and its associated factors among community-dwelling older adults from the "LRGS-Towards Useful Aging (TUA)" longitudinal study. The available data related to cognitive frailty among a sub-sample of older adults aged 60 years and above (n=815) from two states in Malaysia were analysed. In the LRGS-TUA study, a comprehensive interview-based questionnaire was administered to obtain the socio-demographic information of the participants, followed by assessments to examine the cognitive function, functional status, dietary intake, lifestyle, psychosocial status and biomarkers associated with cognitive frailty. The factors associated with cognitive frailty were assessed using a bivariate logistic regression (BLR). The majority of the older adults were categorized as robust (68.4%), followed by cognitively pre-frail (37.4%) and cognitively frail (2.2%). The data on the cognitively frail and pre-frail groups were combined for comparison with the robust group. A hierarchical BLR indicated that advancing age (OR=1.04, 95% CI:1.01-1.08,