Prevalence and Time Trends of Low Serum B12 Levels and Inadequate B12 Dietary Intake in Lebanese Adults amidst the Food Insecurity Situation: Findings from a Nationally Representative Cross-Sectional Study

• Published in: Nutrients 2024-01, Vol.16 (2), p.226
• Main Authors: Hoteit, Maha, Khadra, Razan, Fadlallah, Zahraa, Mourad, Youmna, Chahine, Mohamad, Skaiki, Farouk, Al Manasfi, Elham, Chahine, Abdulrahman, Poh, Omasyarifa Binti Jamal, Tzenios, Nikolaos
• Format: Article
• Language: English
• Subjects: Adult; Adults; Anemia; Animal Feed; Animals; Cross-Sectional Studies; Databases, Factual; Disease prevention; Eating; Ethylenediaminetetraacetic acid; Female; food insecurity; Food security; Gastrointestinal surgery; Households; Humans; intake; Lebanon; Male; Population; Prevalence; Questionnaires; serum level; Small intestine; Sociodemographics; Socioeconomic factors; Veganism; Vegetarianism; vitamin B12; Vitamins
• ISSN: 2072-6643; 2072-6643
• DOI: 10.3390/nu16020226

Rising food insecurity (FI) and the increased prices of animal-based foods could compromise vitamin B12 (B12) intake and serum levels in food-insecure people. Our study aims to determine the prevalence of low levels of serum B12 and its inadequate dietary intake among a nationally representative sample of Lebanese adults aged 18 to 64 years, while exploring the impact of FI and identifying other potential predictors. The B12 intake was assessed using a food frequency questionnaire and the mean of two non-consecutive 24 h recalls. The B12 serum levels were also examined. To examine the time trends in the B12 serum levels and dietary intake, the data from a large representative digitized database of 6290 participants were collected, along with the examination of FAOSTAT food consumption data both before and during the economic crisis period. Our findings revealed that 47.3% of households in Lebanon experienced FI. The inadequate intake of B12 food sources was prevalent in 52.5% of participants, and 61.1% presented with low (23%) or intermediate (38.1%) levels of serum B12. The food-secure households had a higher proportion of B12 intake from meats ( = 0.004), while traditional foods contributed more to food-insecure households ( = 0.000). The participants who were female, unemployed, food-insecure, and had low dietary diversity were about two to three times more likely to have inadequate B12 intake. The predictors of low levels of serum B12 included residing in Beqaa (OR = 2.856 and 95% CI = 1.018-8.01) and having inadequate B12 intake (OR = 1.788 and 95% CI = 1.2-2.65). The findings from observing the time trends in the consumption and the serum levels of B12 indicate a considerable decline in the consumption of most animal-based foods compared to the pre-crisis period, associated with a decline in the serum levels of B12. In conclusion, an alarming prevalence of low dietary intake and low serum levels of B12 was revealed among Lebanese adults, and the indirect effect of FI on B12 serum levels mediated through B12 intake was inferred.