Ziziphus mucronata Willd. (Rhamnaceae): it's botany, toxicity, phytochemistry and pharmacological activities

Ziziphus mucronata is an important multi-purpose plant species that has been used in African traditional medicine for ages in the treatment of various devastating human and animal infections. The current paper is aimed at providing an overview of uses, toxicology, pharmacological properties and phyt...

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Bibliographic Details
Published in:Heliyon 2020-04, Vol.6 (4), p.e03708, Article e03708
Main Authors: Mongalo, N.I., Mashele, S.S., Makhafola, T.J.
Format: Article
Language:English
Subjects:
Agricultural science
Anthelmintic
Antidiabetic
Antimicrobial
Antioxidant
Antiplasmodial
Biological sciences
Chemistry
Cyclopeptides
Ethnomedicinal uses
Food science
Toxicity
Toxicology
Veterinary medicine
Ziziphus mucronate
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Summary:Ziziphus mucronata is an important multi-purpose plant species that has been used in African traditional medicine for ages in the treatment of various devastating human and animal infections. The current paper is aimed at providing an overview of uses, toxicology, pharmacological properties and phytochemistry of Z. mucronata. The information used in the current work was retrieved using various search engines, including Pubmed, Science Direct, Google Scholar, Scielo, SciFinder and Scopus. The key words used included Ziziphus mucronata, secondary metabolites, chemistry, biological activity and pharmacology, anti-inflammatory, antimicrobial, antifungal, antiviral, ethnobotanical survey, medicinal uses, safety, toxicology and other related words. Out of the 46 infections which the plant species is used to treat, the most common uses includes sexually transmitted infections, skin infections, diarrhoea and dysentery, respiratory and chest complaints and gynaecological complaints (citations ≥6). Pharmacologically, the plant species exhibited a potential antimicrobial activity yielding a minimum inhibitory concentration of
ISSN:2405-8440
2405-8440
DOI:10.1016/j.heliyon.2020.e03708