Inducing Peripheral Sympathetic Nerve Activity by Therapeutic Electrical Stimulation

Purpose. To examine whether the activity of peripheral sympathetic nerves in animals with spinal cord injury can be controlled using therapeutic electrical stimulation. Methods. The spinal cords of 6 Wistar rats were severed at T12/T13 disk level and were given continuous therapeutic electrical stim...

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Published in:Journal of orthopaedic surgery (Hong Kong) 2005-08, Vol.13 (2), p.167-170
Main Authors: Mikami, Y, Ogura, T, Kubo, T, Kira, Y, Aramaki, S
Format: Article
Language:English
Subjects:
Animals
Autonomic Pathways - physiology
Disease Models, Animal
Electric Stimulation Therapy
Electrodes, Implanted
Female
Male
Peripheral Nervous System - physiology
Probability
Rats
Rats, Wistar
Risk Factors
Sensitivity and Specificity
Spinal Cord Injuries - therapy
Sympathetic Nervous System - physiology
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container_end_page 170
container_issue 2
container_start_page 167
container_title Journal of orthopaedic surgery (Hong Kong)
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creator Mikami, Y
Ogura, T
Kubo, T
Kira, Y
Aramaki, S
description Purpose. To examine whether the activity of peripheral sympathetic nerves in animals with spinal cord injury can be controlled using therapeutic electrical stimulation. Methods. The spinal cords of 6 Wistar rats were severed at T12/T13 disk level and were given continuous therapeutic electrical stimulation. Microneurography was used to record sympathetic nerve activity at 24, 48, and 72 hours after severing the spinal cord. Results. Integrated values of muscle sympathetic nerve activity after 72 hours of therapeutic electrical stimulation revealed significantly larger potentials on the stimulated side than the non-stimulated side. Skin sympathetic nerve activity showed no difference between the 2 sides. Conclusion. Therapeutic electrical stimulation was found to have a facilitatory effect on the muscle sympathetic nerve activity, whereas regulatory function was activated by the sympathetic nerves.
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To examine whether the activity of peripheral sympathetic nerves in animals with spinal cord injury can be controlled using therapeutic electrical stimulation. Methods. The spinal cords of 6 Wistar rats were severed at T12/T13 disk level and were given continuous therapeutic electrical stimulation. Microneurography was used to record sympathetic nerve activity at 24, 48, and 72 hours after severing the spinal cord. Results. Integrated values of muscle sympathetic nerve activity after 72 hours of therapeutic electrical stimulation revealed significantly larger potentials on the stimulated side than the non-stimulated side. Skin sympathetic nerve activity showed no difference between the 2 sides. Conclusion. Therapeutic electrical stimulation was found to have a facilitatory effect on the muscle sympathetic nerve activity, whereas regulatory function was activated by the sympathetic nerves.</description><identifier>ISSN: 1022-5536</identifier><identifier>EISSN: 2309-4990</identifier><identifier>DOI: 10.1177/230949900501300211</identifier><identifier>PMID: 16131680</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Animals ; Autonomic Pathways - physiology ; Disease Models, Animal ; Electric Stimulation Therapy ; Electrodes, Implanted ; Female ; Male ; Peripheral Nervous System - physiology ; Probability ; Rats ; Rats, Wistar ; Risk Factors ; Sensitivity and Specificity ; Spinal Cord Injuries - therapy ; Sympathetic Nervous System - physiology</subject><ispartof>Journal of orthopaedic surgery (Hong Kong), 2005-08, Vol.13 (2), p.167-170</ispartof><rights>2005 Asia Pacific Orthopaedic Association unless otherwise noted. 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To examine whether the activity of peripheral sympathetic nerves in animals with spinal cord injury can be controlled using therapeutic electrical stimulation. Methods. The spinal cords of 6 Wistar rats were severed at T12/T13 disk level and were given continuous therapeutic electrical stimulation. Microneurography was used to record sympathetic nerve activity at 24, 48, and 72 hours after severing the spinal cord. Results. Integrated values of muscle sympathetic nerve activity after 72 hours of therapeutic electrical stimulation revealed significantly larger potentials on the stimulated side than the non-stimulated side. Skin sympathetic nerve activity showed no difference between the 2 sides. Conclusion. 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To examine whether the activity of peripheral sympathetic nerves in animals with spinal cord injury can be controlled using therapeutic electrical stimulation. Methods. The spinal cords of 6 Wistar rats were severed at T12/T13 disk level and were given continuous therapeutic electrical stimulation. Microneurography was used to record sympathetic nerve activity at 24, 48, and 72 hours after severing the spinal cord. Results. Integrated values of muscle sympathetic nerve activity after 72 hours of therapeutic electrical stimulation revealed significantly larger potentials on the stimulated side than the non-stimulated side. Skin sympathetic nerve activity showed no difference between the 2 sides. Conclusion. 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subjects Animals
Autonomic Pathways - physiology
Disease Models, Animal
Electric Stimulation Therapy
Electrodes, Implanted
Female
Male
Peripheral Nervous System - physiology
Probability
Rats
Rats, Wistar
Risk Factors
Sensitivity and Specificity
Spinal Cord Injuries - therapy
Sympathetic Nervous System - physiology
title Inducing Peripheral Sympathetic Nerve Activity by Therapeutic Electrical Stimulation
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