New Insights about Pulmonary Epithelioid Hemangioendothelioma: Review of the Literature and Two Case Reports

Pulmonary epithelioid hemangioendothelioma (PEH) is a rare neoplasm of vascular origin. There are three different major imaging patterns identified in thoracic manifestation of epithelioid hemangioendothelioma: (1) multiple pulmonary nodules; (2) multiple pulmonary reticulonodular opacities; and (3)...

Full description

Saved in:
Bibliographic Details
Published in:Case reports in radiology 2017-01, Vol.2017 (2017), p.1-14
Main Authors: Pinto, Eugénia, Trinidad, Carmen, Sousa, Marta, Mesquita, Romeu Duarte, Badiola, Iosu Antón
Format: Article
Language:English
Subjects:
Case Report
Case reports
Chemotherapy
Family medical history
Heart surgery
Immunohistochemistry
Literature reviews
Nodules
Oncology
Staining
Thickening
Transcription factors
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Pulmonary epithelioid hemangioendothelioma (PEH) is a rare neoplasm of vascular origin. There are three different major imaging patterns identified in thoracic manifestation of epithelioid hemangioendothelioma: (1) multiple pulmonary nodules; (2) multiple pulmonary reticulonodular opacities; and (3) diffuse infiltrative pleural thickening. Radiographically, presence of bilateral multiple nodules is the most common pattern of presentation. The diagnosis is made on the basis of histopathological findings and confirmed by positive immunohistochemistry staining. Although the prognostic factors for PEH have not yet been well established, a better prognosis is usually associated with the multinodular pattern. We report two different imagological presentations of this rare disease, based on two institutional experiences, along with a review of the relevant literature.
ISSN:2090-6862
2090-6870
DOI:10.1155/2017/5972940