Effect of zinc oxide nanoparticles on physical and antimicrobial properties of resin-modified glass ionomer cement

To improve the limitations, many modifications in the resin-modified glass ionomer (RMGI) composition have been proposed. In this study, we evaluated the effect of different concentrations of zinc oxide (ZnO) nanoparticles incorporated into RMGI cement on its physical and antimicrobial properties. I...

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Bibliographic Details
Published in:Dental research journal 2021, Vol.18 (1), p.73-73
Main Authors: Malekhoseini, Zahra, Rezvani, Mohammad Bagher, Niakan, Mohammad, Atai, Mohammad, Bassir, Mahshid Mohammadi, Alizade, Hamid Safar, Siabani, Saba
Format: Article
Language:English
Subjects:
flexural strength
fluorides
glass ionomer cements
microbial sensitivity tests
Original
zinc oxide
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Summary:To improve the limitations, many modifications in the resin-modified glass ionomer (RMGI) composition have been proposed. In this study, we evaluated the effect of different concentrations of zinc oxide (ZnO) nanoparticles incorporated into RMGI cement on its physical and antimicrobial properties. In this study, ZnO nanoparticles with 0-4 wt.% concentrations were incorporated into RMGI. The following tests were carried out: (a) Antibacterial activity against tested by disc diffusion method, (b) mechanical behavior assessment by measuring flexural strength (FS) and flexural modulus (FM), (c) micro-shear bond strength (μ-SBS), and (d) fluoride and zinc release. Data were analyzed using the statistical tests of ANOVA, -test, and Tukey's HSD c in SPSS V22. The level of significancy was 0.05. In the disc diffusion method, specimens with 2 wt.% ZnO nanoparticles showed the highest antimicrobial efficacy ( < 0.05). After 1 month of water storage, no significant difference was observed in FS and FM of the samples ( > 0.05). In 2 wt.% ZnO nanoparticles group, μSBS increased in the first 7 days but decreased by 17% after one month, which showed a significant difference with that of the control group. The fluoride release did no change in the ZnO nanoparticle-containing group compared with the control group at all time intervals. Incorporation of 2 wt.% ZnO nanoparticles into the RMGI cement adds antimicrobial activity to the cement without sacrificing FS and fluoride release properties, while decreased μSBS.
ISSN:1735-3327
2008-0255
DOI:10.4103/1735-3327.326646