Clinical value of the Systemic Inflammatory Response Index for predicting acute pancreatitis severity in Vietnamese setting

Background and Aim Accurate prediction of severe acute pancreatitis (SAP) is crucial for timely intervention. This study focuses on the Systemic Inflammatory Response Index (SIRI) to assess its clinical value in predicting the severity of AP in the Vietnamese context. Methods A cross‐sectional prosp...

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Bibliographic Details
Published in:JGH open 2024-06, Vol.8 (6), p.e13101-n/a
Main Authors: Dao, Yen H T, Huynh, Tien M, Tran, Duy T, Ho, Phat T, Vo, Thong D
Format: Article
Language:English
Subjects:
acute pancreatitis
Alcohol
Bedside Index for Severity in Acute Pancreatitis
Blood tests
Creatinine
Cysts
Inflammation
Laboratories
Lymphocytes
Medical prognosis
Mortality
Neutrophils
Original
Pancreatitis
Patients
Pleural effusion
prognosis
Systemic Inflammatory Response Index
Vietnam
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Summary:Background and Aim Accurate prediction of severe acute pancreatitis (SAP) is crucial for timely intervention. This study focuses on the Systemic Inflammatory Response Index (SIRI) to assess its clinical value in predicting the severity of AP in the Vietnamese context. Methods A cross‐sectional prospective study was conducted with acute pancreatitis patients at a national hospital in Ho Chi Minh City. The patients were classified into nonsevere and severe groups, and the clinical characteristics were analyzed. The predictive abilities of SIRI, calculated using neutrophil × monocyte/lymphocyte, was assessed for predictive abilities. Multivariate regression and receiver operating characteristics (ROC) curves evaluated the prognostic factors and predictive accuracy. Results Among 207 patients, 78.7% had nonsevere AP, and 21.3% had SAP. The severe group exhibited a significantly higher median SIRI (12.0) than the nonsevere group (4.9) (P 
ISSN:2397-9070
2397-9070
DOI:10.1002/jgh3.13101