A case of pterygium-like proliferation containing postoperative limbal dermoid remnants: a clinicopathological study

This study reports a case of pterygium-like proliferation containing postoperative limbal dermoid remnants and its clinicopathological features. A 79-year-old Japanese woman, with a history of congenital limbal dermoid resection at age 12, presented with a pterygium-like tissue growth in the left ey...

Full description

Saved in:
Bibliographic Details
Published in:BMC ophthalmology 2021-01, Vol.21 (1), p.12-12, Article 12
Main Authors: Mitamura, Mizuho, Kase, Satoru, Ohguchi, Takeshi, Ishida, Susumu
Format: Article
Language:English
Subjects:
Adipose tissue
Adipose tissues
Aged
Case Report
Case reports
Cell growth
Cell Proliferation
Child
Collagen
Congenital diseases
Conjunctiva
Consent
Degeneration
Dermoid Cyst - surgery
Endothelial Cells
Epithelial cells
Female
Fibers
Genetic disorders
Histopathology
Humans
Ki67
Limbal dermoid
Metaplasia
Neoplasm Recurrence, Local
Ophthalmology
Peripheral nerves
Pterygium
Pterygium - surgery
Stem cells
Surgery
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This study reports a case of pterygium-like proliferation containing postoperative limbal dermoid remnants and its clinicopathological features. A 79-year-old Japanese woman, with a history of congenital limbal dermoid resection at age 12, presented with a pterygium-like tissue growth in the left eye. Its temporal location and marked thickness with abundant fatty droplets were atypical of primary pterygium. We performed pterygium surgery and ocular surface reconstruction. Pathological findings included squamous metaplasia, neovessels, and elastic degeneration, as well as prominent subepithelial and stromal accumulation of collagen fibers, adipose tissue formation, and presence of a peripheral nerve corresponded with the frequent findings of limbal dermoid. Ki67, a marker for cell proliferation, was immunopositive in pterygial epithelial cells and neovascular endothelial cells, but not in dermoid components. Although the pathological finding of degenerative elastic fibers indicated the common feature of ultraviolet-induced pterygium, clinical appearances were atypical possibly due to modification with dermoid remnants.
ISSN:1471-2415
1471-2415
DOI:10.1186/s12886-020-01767-5