Effect of platelet-rich plasma versus steroid injection in plantar fasciitis: a randomized clinical trial

Plantar fasciitis (PF) is a common orthopaedic problem, with heel pain worsening the quality of life. Although steroid injection is often used if the conservative treatment fails, Platelet-Rich Plasma (PRP) injection is gaining popularity due to its safety and long-lasting effect. However, the effec...

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Published in:BMC musculoskeletal disorders 2023-03, Vol.24 (1), p.172-11, Article 172
Main Authors: Sharma, Rachit, Chaudhary, Narendra Kumar, Karki, Mandeep, Sunuwar, Dev Ram, Singh, Devendra Raj, Pradhan, Pranil Man Singh, Gyawali, Prakash, Duwal Shrestha, Sailendra Kumar, Bhandari, Kailash Kumar
Format: Article
Language:English
Subjects:
Ankle
Arthritis
Behavior Therapy
Biomechanics
Blood platelets
Care and treatment
Clinical trials
Developing countries
Diagnosis
Dosage and administration
Fascia
Fasciitis
Fasciitis, Plantar - drug therapy
Hospitals
Humans
Hyaluronic acid
Injection
Laboratories
LDCs
Orthopedics
Pain
Patient outcomes
Plantar fascia
Plantar fasciitis
Plasma
Platelet-Rich Plasma
Platelet-rich plasma therapy
Platelets
Quality of Life
Statistical analysis
Steroid
Steroids
Steroids (Drugs)
Surgery
Testing
Trauma
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Summary:Plantar fasciitis (PF) is a common orthopaedic problem, with heel pain worsening the quality of life. Although steroid injection is often used if the conservative treatment fails, Platelet-Rich Plasma (PRP) injection is gaining popularity due to its safety and long-lasting effect. However, the effect of PRP versus steroid injection in PF has not been studied yet in Nepal. Therefore, this study aimed to assess the effect of PRP compared with steroid injection in the treatment of PF. This study was a single-center, hospital-based, open-label, parallel-group randomized clinical trial to compare the effect of PRP injection with steroid injection in plantar fasciitis between August 2020 and March 2022. A total of 90 randomly selected participants aged 18 to 60 years suffering from plantar fasciitis with failed conservative treatment were intervened. The American Orthopaedic Foot and Ankle Society (AOFAS) and the Visual Analog Scale (VAS) scoring system were used to evaluate functional mobility and pain before and after the intervention for three and six months, respectively. Statistical analyses were performed using a Student's two-sample t-test. P-value 
ISSN:1471-2474
1471-2474
DOI:10.1186/s12891-023-06277-1