MICROBIOLOGICAL ANALYSIS OF BILE IN PATIENTS WITH BENIGN AND MALIGNANT BILIOPANCREATIC DISEASES AND ITS CONSEQUENCES

• Published in: Arquivos de gastroenterologia 2016-07, Vol.53 (3), p.156-162
• Main Authors: Alves, José Roberto, Silva, Rodrigo do Carmo, Guerra, Sâmea Costa Pinheiro, Freitas, Tiago Tavares de, Souza, Dyego Leandro Bezerra de, Amico, Enio Campos
• Format: Article
• Language: English
• Subjects: Adenocarcinoma - microbiology; Adenocarcinoma - surgery; Adult; Aged; Aged, 80 and over; Ampulla of Vater - microbiology; Ampulla of Vater - surgery; Bile; Bile - microbiology; Carcinogênese; Choledocholithiasis - microbiology; Choledocholithiasis - surgery; Colecistectomia; Common Bile Duct Neoplasms - microbiology; Common Bile Duct Neoplasms - surgery; Complicações pós-operatórias; Escherichia coli - isolation & purification; Female; Fever - surgery; GASTROENTEROLOGY & HEPATOLOGY; Humans; Klebsiella - isolation & purification; Male; Microbiologia; Middle Aged; Postoperative Complications; Retrospective Studies; Streptococcus - isolation & purification; Young Adult
• ISSN: 0004-2803; 1678-4219; 1678-4219; 0004-2803
• DOI: 10.1590/S0004-28032016000300007

Bactibilia has several consequences to human health. Assessing the bile microbiology of patients with biliopancreatic diseases in order to identify bacteria and their possible infectious complications. Retrospective study of 30 bile culture samples from patients with benign and malignant biliopancreatic diseases. The samples were assessed to set the bile microbiological flora and to search for its possible link with comorbidity, carcinogenesis and postoperative infectious complications. Thirty bile samples from patients at mean age ≈57.7 years, mostly female (n=18), were assessed. Bactibilia was found in 12 cases, mostly in patients with benign diseases (n=8), older than 50 years (n=23) and female (n=10). Adenocarcinoma of the duodenal papilla (n=9) and cholelithiasis (n=8) were the most common diseases. Escherichia coli (n=5) and Klebsiella sp (n=3) were predominantly found in patients with benign diseases; and Klebsiella sp (n=2) and Streptococcus sp (n=2) were prevalent in cancer patients. There were postoperative infectious complications in seven cases, five of them in bactibilia-associated patients (P=0.084). Bactibilia was found in 12 samples and Escherichia coli and Klebsiella sp were most often identified in patients with benign diseases, as well as Streptococcus sp and Klebsiella sp in cancer patients. There was a trend of higher postoperative infectious complication incidence in patients with bactibilia.