Facilitation of Vaginal Delivery in an Infant with Complete Heart Block Secondary to Maternal Anti-Ro Antibodies

Congenital heart block (CHB) is a rare disorder that may be associated with a high morbidity and even mortality, with a risk of death both in utero and during infancy. Women with serum titres of anti-Ro and/or anti-La antibodies carry a risk of CHB of 1–5% in their offspring, with a recurrence risk...

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Bibliographic Details
Published in:Case reports in obstetrics and gynecology 2017-01, Vol.2017 (2017), p.1-4
Main Authors: Bruce, I., Shebani, S., Tripathi, L., Thornton, E., Byrd, L.
Format: Article
Language:English
Subjects:
Antibodies
Anticoagulants
Cardiac arrhythmia
Cardiology
Cardiovascular agents
Cardiovascular disease
Case Report
Case reports
Childbirth
Congenital diseases
Genetic disorders
Gynecology
Health risk assessment
Heart block
Heart failure
Hospitals
Immunoglobulins
Lupus
Mortality
Obstetrics
Pregnancy
Viral antibodies
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Summary:Congenital heart block (CHB) is a rare disorder that may be associated with a high morbidity and even mortality, with a risk of death both in utero and during infancy. Women with serum titres of anti-Ro and/or anti-La antibodies carry a risk of CHB of 1–5% in their offspring, with a recurrence risk of approximately 20%. We present a case of a 36-year-old female with a pregnancy complicated by congenital heart block. Autoimmune profiling at booking showed she was positive for lupus anticoagulant and anti-Ro antibodies. A fetal echocardiogram at 21 + 3 showed complete heart block. She was monitored throughout the remainder of her pregnancy with serial growth scans, cardiovascular profiling, and BPP scoring. She had a normal vaginal delivery at term to a female infant.
ISSN:2090-6684
2090-6692
DOI:10.1155/2017/8352320