Inflammation, Appetite and Food Intake in Older Hospitalized Patients

The effect of inflammation on appetite and food intake has been rarely studied in humans. In this study, we examined the association of C-reactive protein (CRP), as an inflammatory marker, with appetite and food intake among older hospitalized patients. A total of 200 older individuals, who were con...

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Bibliographic Details
Published in:Nutrients 2019-08, Vol.11 (9), p.1986
Main Authors: Sieske, Lars, Janssen, Gregor, Babel, Nina, Westhoff, Timm Henning, Wirth, Rainer, Pourhassan, Maryam
Format: Article
Language:English
Subjects:
Age Factors
Aged
Aged, 80 and over
Aging
Anorexia
Appetite
Appetite loss
Biomarkers - blood
Body weight loss
C-reactive protein
C-Reactive Protein - analysis
Eating
Energy balance
Energy requirements
Feeding Behavior
Female
Food
Food intake
Frailty
Gastrointestinal surgery
Geriatric Assessment
Geriatrics
Hemodialysis
Hospitalization
Hospitals
Humans
Inflammation
Inflammation - blood
Inflammation - diagnosis
Inflammation - psychology
Inflammation Mediators - blood
Inpatients - psychology
Male
Malnutrition
Malnutrition - blood
Malnutrition - diagnosis
Malnutrition - psychology
Mental depression
Neurosciences
Nutrient deficiency
Nutrient loss
Nutrition
Nutritional Status
Older people
older persons
Parenteral nutrition
Patients
Prospective Studies
Proteins
Questionnaires
Risk Factors
Sarcopenia
Systematic review
Weight loss
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Summary:The effect of inflammation on appetite and food intake has been rarely studied in humans. In this study, we examined the association of C-reactive protein (CRP), as an inflammatory marker, with appetite and food intake among older hospitalized patients. A total of 200 older individuals, who were consecutively admitted to a geriatric acute care ward, participated in this prospective observational study. Appetite was evaluated using the Edmonton Symptom Assessment System (ESAS) and the Simplified Nutritional Appetite Questionnaire (SNAQ), respectively. Food intake was measured according to plate diagram method and participants were categorized as having food intake 3.0 (mg/dL) were considered as moderate to severe inflammation. Of total population with mean age 81.4 ± 6.6 years (62.5% females), 51 (25.5%) had no inflammation and 88 (44.0%) and 61 (30.5%) had mild and moderate to severe inflammation, respectively. According to MNA-SF, 9.0% and 60.0% had normal nutritional status or a risk of malnutrition, respectively, whereas 31.0% were malnourished. Based on the SNAQ-appetite-question, 32.5% of the patients demonstrated poor and very poor appetite whereas 23.5% reported severe loss of appetite according to ESAS. Ninety-five (48.0%) of the participants had food intake
ISSN:2072-6643
2072-6643
DOI:10.3390/nu11091986