Regioselective alkynylation followed by Suzuki coupling of 2,4-dichloroquinoline: synthesis of 2-alkynyl-4-arylquinolines

A two step synthesis of 2-alkynyl-4-arylquinolines has been accomplished via Pd/C-mediated regioselective C-2 alkynylation of 2,4-dichloroquinoline in water followed by Suzuki coupling at C-4 of the resulting 4-chloro derivative.

Saved in:
Bibliographic Details
Published in:Beilstein journal of organic chemistry 2009-07, Vol.5 (1), p.32-32
Main Authors: Reddy, Ellanki Amarender, Islam, Aminul, Mukkanti, K, Bandameedi, Venkanna, Bhowmik, Dipal Ranjan, Pal, Manojit
Format: Article
Language:English
Subjects:
2,4-dichloroquinoline
alkyne
boronic acid
catalysis
Chemistry
palladium
Preliminary Communication
water
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A two step synthesis of 2-alkynyl-4-arylquinolines has been accomplished via Pd/C-mediated regioselective C-2 alkynylation of 2,4-dichloroquinoline in water followed by Suzuki coupling at C-4 of the resulting 4-chloro derivative.
ISSN:1860-5397
1860-5397
DOI:10.3762/bjoc.5.32