Different age-independent effects of nutraceutical combinations on endothelium-mediated coronary flow reserve

Some components of Nutraceuticals (NUT) such as red yeast rice and have demonstrated positive effects on the endothelial function in hypercholesterolemic subjects. Our aim was to compare the effects of two different NUT combinations on cold pressure test (CPT) derived coronary flow reserve (CFR) ass...

Full description

Saved in:
Bibliographic Details
Published in:Immunity & ageing 2018-11, Vol.15 (1), p.30-30, Article 30
Main Authors: Esposito, Roberta, Sorrentino, Regina, Giugliano, Giuseppe, Avvedimento, Marisa, Paolillo, Roberta, Santoro, Ciro, Scalamogna, Maria, Esposito, Mafalda, Ilardi, Federica, Rozza, Francesco, Esposito, Giovanni, Galderisi, Maurizio, Trimarco, Valentina
Format: Article
Language:English
Subjects:
Age
Analysis
Berberine
Blood glucose
Blood platelets
Blood pressure
Cardiovascular disease
Cardiovascular diseases
Cholesterol
Cholesterol-lowering
Clinical trials
Cold pressure test
Coronary artery
Coronary flow reserve
Coronary vessels
Emolument
Endothelial function
Endothelium
Flow velocity
Functional foods & nutraceuticals
Health risk assessment
Heart
Heart diseases
Heart rate
Inflammatory diseases
Lipids
Low density lipoprotein
Metabolism
Morus alba
Movie propaganda
Nutraceutical therapy
Platelet aggregation
Powder
Risk factors
Yeast
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Some components of Nutraceuticals (NUT) such as red yeast rice and have demonstrated positive effects on the endothelial function in hypercholesterolemic subjects. Our aim was to compare the effects of two different NUT combinations on cold pressure test (CPT) derived coronary flow reserve (CFR) assessed by transthoracic echo-Doppler. In a randomized, single-blind study, 28 consecutive patients with a variety of cardiovascular risk factors received NUT A (LopiGLIK®: berberine, red yeast rice powder, and leaf extract of ) or B (Armolipid Plus®: policosanol, red yeast rice, berberine, astaxantine, folic acidandcoenzyme Q10). An echo-Doppler exam with evaluation of CFR was performed at baseline, 2 h (acute test) and 30 days after daily NUT assumption. Blood sampling for metabolic profile and platelet aggregometry was performed at baseline and after 30 days of daily NUT assumption. CFR was not significantly modified at the acute test. After 30 days, CFR improved with NUT A (  
ISSN:1742-4933
1742-4933
DOI:10.1186/s12979-018-0138-3