A Case of Autoimmune Encephalitis with Refractory Status Epilepticus

Refractory status epilepticus is usually caused by a severe brain injury and has a high rate of mortality and morbidity despite the infusion of antiepileptic drugs and anesthetic agents. Autoimmune encephalitis is one cause of refractory status epilepticus and status epilepticus may be the initial s...

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Bibliographic Details
Published in:Archives of Epilepsy 2019-01, Vol.25 (3), p.165-168
Main Authors: Merve Melodi ÇAKAR, Aslıhan AKŞAR, Meliha AKPINAR, Elif MERCAN, Sezgin KEHAYA, Babürhan GÜLDİKEN
Format: Article
Language:English
Subjects:
immunotherapy
intravenous immunoglobulin
pareneoplastic limbic encephalitis
status epilepticus
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Summary:Refractory status epilepticus is usually caused by a severe brain injury and has a high rate of mortality and morbidity despite the infusion of antiepileptic drugs and anesthetic agents. Autoimmune encephalitis is one cause of refractory status epilepticus and status epilepticus may be the initial symptom. The seizures are generally resistant to standard treatment and may require immunotherapeutics. This is a description of a patient who had refractory status epilepticus despite appropriate doses of antiepileptic and general anesthetic drugs, but responded to intravenous immunoglobulin therapy. Examinations revealed an ovarian teratoma with a negative serum N-methyl-D-aspartate receptor antibody.
ISSN:2792-0550
DOI:10.14744/epilepsi.2019.91259