A Case of Autoimmune Encephalitis with Refractory Status Epilepticus

Refractory status epilepticus is usually caused by a severe brain injury and has a high rate of mortality and morbidity despite the infusion of antiepileptic drugs and anesthetic agents. Autoimmune encephalitis is one cause of refractory status epilepticus and status epilepticus may be the initial s...

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Published in:Archives of Epilepsy 2019-01, Vol.25 (3), p.165-168
Main Authors: Merve Melodi ÇAKAR, Aslıhan AKŞAR, Meliha AKPINAR, Elif MERCAN, Sezgin KEHAYA, Babürhan GÜLDİKEN
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Language:English
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immunotherapy
intravenous immunoglobulin
pareneoplastic limbic encephalitis
status epilepticus
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container_end_page 168
container_issue 3
container_start_page 165
container_title Archives of Epilepsy
container_volume 25
creator Merve Melodi ÇAKAR
Aslıhan AKŞAR
Meliha AKPINAR
Elif MERCAN
Sezgin KEHAYA
Babürhan GÜLDİKEN
description Refractory status epilepticus is usually caused by a severe brain injury and has a high rate of mortality and morbidity despite the infusion of antiepileptic drugs and anesthetic agents. Autoimmune encephalitis is one cause of refractory status epilepticus and status epilepticus may be the initial symptom. The seizures are generally resistant to standard treatment and may require immunotherapeutics. This is a description of a patient who had refractory status epilepticus despite appropriate doses of antiepileptic and general anesthetic drugs, but responded to intravenous immunoglobulin therapy. Examinations revealed an ovarian teratoma with a negative serum N-methyl-D-aspartate receptor antibody.
doi_str_mv 10.14744/epilepsi.2019.91259
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subjects immunotherapy
intravenous immunoglobulin
pareneoplastic limbic encephalitis
status epilepticus
title A Case of Autoimmune Encephalitis with Refractory Status Epilepticus
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