Para testicular rhabdomyosarcoma in adults: three case reports and review of literature

Paratesticular embryonal rhabdomyosarcoma (RMS) is a rare tumor arising from the mesenchymal tissues of the spermatic cord, epididymis, testis and testicular tunics. We report three cases of adult paratesticular RMS, two embryonic and one pleomorphic rhabdomyosarcoma. All the patients underwent diag...

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Bibliographic Details
Published in:The Pan African medical journal 2014-11, Vol.19 (279), p.279-279
Main Authors: Boudahna, Lamiae, Benbrahim, Zineb, Amaadour, Lamiae, Mazouz, Aicha, Benhayoune, Khadija, Tahiri, Yassir, Farih, Moulay Hassan, Amarti, Afaf, Arifi, Samia, Mellas, Nawfel
Format: Article
Language:English
Subjects:
Adolescent
Adult
adults
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Case Report
Humans
Male
Orchiectomy - methods
para testicular rhabdomyosarcoma
Practice Guidelines as Topic
Rhabdomyosarcoma - diagnosis
Rhabdomyosarcoma - pathology
Rhabdomyosarcoma - therapy
Testicular Neoplasms - diagnosis
Testicular Neoplasms - pathology
Testicular Neoplasms - therapy
Treatment Outcome
tumor
Young Adult
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Summary:Paratesticular embryonal rhabdomyosarcoma (RMS) is a rare tumor arising from the mesenchymal tissues of the spermatic cord, epididymis, testis and testicular tunics. We report three cases of adult paratesticular RMS, two embryonic and one pleomorphic rhabdomyosarcoma. All the patients underwent diagnostic orchidectomy. The work up investigations revealed lung metastases. Chemotherapy with Ifosfamide and Doxorubicin was used in two cases, whereas Vincristin-Actinomycin D and Cyclophosphamide was received in one case. An objective partial response was reported in 2 cases, with complete response in one case. Paratesticular RMS is a rare and aggressive tumor. Because of the absence of protocols designed specifically for adult patients, it is necessary to follow therapeutic guidelines in pediatric protocols.
ISSN:1937-8688
1937-8688
DOI:10.11604/pamj.2014.19.279.4784