Periodontal disease and bacterial vaginosis increase the risk for adverse pregnancy outcome

• Published in: Infectious diseases in obstetrics and gynecology 2005, Vol.13 (4), p.213-216
• Main Authors: Oittinen, Juha, Kurki, Tapio, Kekki, Minnamaija, Kuusisto, Minna, Pussinen, Pirkko, Vilkuna-Rautiainen, Tiina, Nieminen, Anja, Asikainen, Sirkka, Paavonen, Jorma
• Format: Article
• Language: English
• ISSN: 1064-7449; 1098-0997; 1098-0997
• DOI: 10.1080/10647440500240730

To determine whether periodontal disease or bacterial vaginosis (BV) diagnosed before pregnancy increase the risk for adverse pregnancy outcome.OBJECTIVESTo determine whether periodontal disease or bacterial vaginosis (BV) diagnosed before pregnancy increase the risk for adverse pregnancy outcome.We enrolled a total of 252 women who had discontinued contraception in order to become pregnant. The first 130 pregnant women were included in the analyses.METHODSWe enrolled a total of 252 women who had discontinued contraception in order to become pregnant. The first 130 pregnant women were included in the analyses.Multivariate analysis showed a strong association between periodontal disease and adverse pregnancy outcome (OR 5.5, 95% confidence interval 1.4-21.2; p = 0.014), and a borderline association between BV and adverse pregnancy outcome (OR 3.2, 95% confidence interval 0.9-10.7; p = 0.061).RESULTSMultivariate analysis showed a strong association between periodontal disease and adverse pregnancy outcome (OR 5.5, 95% confidence interval 1.4-21.2; p = 0.014), and a borderline association between BV and adverse pregnancy outcome (OR 3.2, 95% confidence interval 0.9-10.7; p = 0.061).Our study suggests that pre-pregnancy counseling should include both oral and vaginal examinations to rule out periodontal disease and BV. This may ultimately have an impact on antenatal healthcare, and decrease the risk for adverse pregnancy outcome.CONCLUSIONOur study suggests that pre-pregnancy counseling should include both oral and vaginal examinations to rule out periodontal disease and BV. This may ultimately have an impact on antenatal healthcare, and decrease the risk for adverse pregnancy outcome.