Juvenile Xanthogranuloma as Differential Diagnosis of a Vulvar Mass: A Case Report

Abstract Vulvar masses in children are an unusual finding but their differential diagnosis is extensive. In case of solid masses, rhabdomyosarcoma (RMS) must always be considered due to the fact that it is the most common tumor in external genitals during childhood. However, RMS has a radiological a...

Full description

Saved in:
Bibliographic Details
Published in:European journal of pediatric surgery reports 2022-01, Vol.10 (1), p.e25-e29
Main Authors: Bada Bosch, Isabel, Cañizo, Agustín del, Campos-Domínguez, Minia, Ordoñez, Javier, Blanco Verdú, María Dolores, Fanjul, María, Pérez-Egido, Laura, de Agustín, Juan Carlos
Format: Article
Language:English
Subjects:
Case Report
juvenile xanthogranuloma
rhabdomyosarcoma
vulvar mass
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Vulvar masses in children are an unusual finding but their differential diagnosis is extensive. In case of solid masses, rhabdomyosarcoma (RMS) must always be considered due to the fact that it is the most common tumor in external genitals during childhood. However, RMS has a radiological appearance very similar to juvenile xanthogranuloma (JXG). We present a 16-month-old girl with a 2 cm solid mass on her left labia majora, with four overlying cutaneous papules. After imaging tests, an excisional biopsy was programmed due to high malignancy suspicion. Histopathology of the mass and one of the papules was diagnostic for JXG. After a 12-month follow-up, the patient shows no signs of relapse or complication. Deep JXG is an uncommon entity in childhood and exceptional in the genital area. Therefore, it must be included in the differential diagnosis of a solid vulvar mass, especially if accompanying yellowish xanthomatous cutaneous lesions are present.
ISSN:2194-7619
2194-7627
DOI:10.1055/s-0042-1743159