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The association between hyperuricemia and atrial fibrillation recurrence after catheter ablation

Background Hyperuricemia (HU) has been reported to be associated with a high incidence of atrial fibrillation (AF). However, the relationship between HUA and recurrent AF after catheter ablation (CA) is unclear. Methods Four hundred consecutive AF patients (paroxysmal/persistent AF [PAF/PsAF]: 200/2...

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Published in:Journal of arrhythmia 2024-06, Vol.40 (3), p.520-526
Main Authors: Oseto, Hirotsuna, Yamashita, Seigo, Tokuda, Michifumi, Sato, Hidenori, Shiomi, Satoko, Sakurai, Ryutaro, Yokoyama, Masaaki, Tokutake, Kenichi, Katoh, Mika, Miyanaga, Satoru, Yoshimura, Michihiro, Yamane, Teiichi
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Language:English
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Summary:Background Hyperuricemia (HU) has been reported to be associated with a high incidence of atrial fibrillation (AF). However, the relationship between HUA and recurrent AF after catheter ablation (CA) is unclear. Methods Four hundred consecutive AF patients (paroxysmal/persistent AF [PAF/PsAF]: 200/200) who underwent the initial CA were retrospectively enrolled. HU was defined as serum uric acid (SUA) level >7.0 mg/dL. We measured SUA levels 1 day before (pre‐CA) and 1 month after CA (post‐CA). A second‐generation 28 mm cryoballoon was used for pulmonary vein isolation (PVI) for PAF, while PVI plus linear ablation (roof and mitral isthmus lines) by radiofrequency catheter was conducted for PsAF. Results During 57 ± 24 months of follow‐up, AF recurred in 16% and 42% in PAF and PsAF patients (p 
ISSN:1880-4276
1883-2148
DOI:10.1002/joa3.13030