介入放射学:代谢性疾病治疗手段的新补充

Abstract The rising prevalence of metabolic disorders such as obesity and type 2 diabetes mellitus (T2DM) poses a major challenge to global health. Existing therapeutic approaches have limitations, and there is a need for new, safe, and less invasive treatments. Interventional metabolic therapy is a...

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Bibliographic Details
Published in:Journal of diabetes 2023-08, Vol.15 (8), p.665-673
Main Authors: Zhi Wang, Dan‐Qi Zhu, Xiang‐Yun Zhu, De‐Chen Liu, Qing‐Yue Cao, Tao Pan, Qi Zhang, Xiao‐Chun Gu, Ling Li, Gao‐Jun Teng
Format: Article
Language:English
Subjects:
2型糖尿病
代谢干预
代谢紊乱
肥胖
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Summary:Abstract The rising prevalence of metabolic disorders such as obesity and type 2 diabetes mellitus (T2DM) poses a major challenge to global health. Existing therapeutic approaches have limitations, and there is a need for new, safe, and less invasive treatments. Interventional metabolic therapy is a new addition to the treatment arsenal for metabolic disorders. This review focuses on two interventional techniques: bariatric arterial embolization (BAE) and endovascular denervation (EDN). BAE involves embolizing specific arteries feeding ghrelin‐producing cells to suppress appetite and promote weight loss. EDN targets nerves that regulate metabolic organs to improve glycemic control in T2DM patients. We describe the current state of these techniques, their mechanisms of action, and the available safety and effectiveness data. We also propose a new territory called “Interventional Metabology” to encompass these and other interventional approaches to treating metabolic disorders.
ISSN:1753-0393
1753-0407
DOI:10.1111/1753-0407.13437