Chemical composition, antimicrobial and antioxidant properties of Mentha longifolia (L.) Huds. essential oil

Introduction: Present study describes the antimicrobial activity and free radical scavenging capacity (RSC) of essential oil from Mentha longifolia (L.) Huds. Aim of this study to investigate the quality, antimicrobial and antioxidant activity of wild species Mentha longifolia essential oil from Bos...

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Bibliographic Details
Published in:Journal of Health Sciences (Sarajevo) 2012-12, Vol.2 (3)
Main Authors: Haris Nikšić, Elvira Kovač Bešović, Elma Makarević, Kemal Durić
Format: Article
Language:English
Subjects:
antimicrobial activity
antioxidant activity
chemical composition
essential oil
Mentha longifolia (L.) Huds
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Summary:Introduction: Present study describes the antimicrobial activity and free radical scavenging capacity (RSC) of essential oil from Mentha longifolia (L.) Huds. Aim of this study to investigate the quality, antimicrobial and antioxidant activity of wild species Mentha longifolia essential oil from Bosnia and Herzegovina. Methods: The chemical profi le of essential oil was evaluated by the means of gas chromatography-mass spectrometry (GC-MS) and thin-layer chromatography (TLC). Antimicrobial activity was tested against 6 bacterial strains. RSC was assessed by measuring the scavenging activity of essential oils on 2,2- diphenyl-1-picrylhydrazil (DPPH). Results: The main constituents of the essential oil of M. longifoliae folium were oxygenated monoterpenes,piperitone oxide (63.58%) and 1,8-cineole (12.03%). Essential oil exhibited very strong antibacterial activity.The most important antibacterial activity essential oil was expressed on Gram negative strains: Escherichia coli, Pseudomonas aerginosa and Salmonella enterica. subsp.enterica serotype ABONY. Antioxidant activity was evaluated as a RSC. Investigated essential oil was able to reduce DPPH radicals into the neutral DPPHH form (IC50=10.5 μg/ml) and this activity was dose –dependent. Conclusion: The study revealed signifi cant antimicrobial activity of the investigated essential oil. The examined oil exhibited high RSC, which was found to be in correlation to the content of mainly monoterpene ketones and aldehydes. These results indicate that essential oils could serve as safe antioxidant and antiseptic supplements in pharmaceuticals.
ISSN:2232-7576
1986-8049
DOI:10.17532/jhsci.2012.38