Cognitive function in multiple sclerosis: a subcortical pattern of neuropsychological impairment?

In order to evaluate cognitive impairment in multiple sclerosis (MS) neuropsychological tests were administered to 25 patients with clinically definite disease. Four (16%) showed diffuse cognitive impairment, whereas the others, compared with controls showed a specific deficit on tests known to be s...

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Bibliographic Details
Published in:Behavioural neurology 1991, Vol.4 (3), p.129-141
Main Authors: Caltagirone, C, Carlesimo, G A, Fadda, L, Roncacci, S
Format: Article
Language:English
Online Access:Get full text
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Summary:In order to evaluate cognitive impairment in multiple sclerosis (MS) neuropsychological tests were administered to 25 patients with clinically definite disease. Four (16%) showed diffuse cognitive impairment, whereas the others, compared with controls showed a specific deficit on tests known to be sensitive to frontal lobe damage. These results are interpreted in the light of current hypotheses relating to subcortical contributions in cognition.
ISSN:0953-4180
1875-8584
DOI:10.3233/BEN-1991-4301