Heart Retransplant Recipients Have Better Survival With Concurrent Kidney Transplant Than With Heart Retransplant Alone

Heart retransplant (HRT) recipients represent a growing number of transplant patients. The impact of concurrent kidney transplants (KTs) in this population has not been well studied. We tested the hypothesis that recipients of HRT with concurrent KT (HRT-KT) would have worse survival than recipients...

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Bibliographic Details
Published in:Journal of the American Heart Association 2015-12, Vol.4 (12), p.n/a
Main Authors: Savla, Jill, Lin, Kimberly Y, Pradhan, Madhura, Ruebner, Rebecca L, Rogers, Rachel S, Haskins, Somaly S, Owens, Anjali T, Abt, Peter, Gaynor, J William, Shaddy, Robert E, Rossano, Joseph W
Format: Article
Language:English
Subjects:
Adult
Age Factors
Female
Glomerular Filtration Rate
heart
Heart Transplantation - mortality
Humans
Kaplan-Meier Estimate
kidney
Kidney Diseases - surgery
Kidney Transplantation - mortality
Male
Middle Aged
Original Research
Reoperation
Retrospective Studies
Risk Factors
survival
Survival Analysis
transplantation
Waiting Lists
Young Adult
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Summary:Heart retransplant (HRT) recipients represent a growing number of transplant patients. The impact of concurrent kidney transplants (KTs) in this population has not been well studied. We tested the hypothesis that recipients of HRT with concurrent KT (HRT-KT) would have worse survival than recipients of HRT alone. A retrospective analysis of the United Network of Organ Sharing database was performed for all patients undergoing HRT from 1987 to 2011. There were 1660 HRT patients, of which 116 (7%) received concurrent KT. Those who received HRT-KT had older age, longer wait-list time, worse kidney function, and more known diabetes. Survival among recipients of HRT-KT was significantly better than that of recipients of HRT alone (P=0.005). A subgroup of 323 HRT patients with severe kidney dysfunction (estimated glomerular filtration rate
ISSN:2047-9980
2047-9980
DOI:10.1161/JAHA.115.002435