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Urinary and fecal incontinence during levetiracetam therapy

Other mechanisms include inhibition of Zn2 + -associated negative gama-aminobutyric acid (GABA) modulation, high-voltage-gated N-type Ca2 + channel currents, and GABA release. There was no evidence of urinary and gastoinintestinal tract infection, and no evidence central nervous system involvement i...

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Bibliographic Details
Published in:Annals of the Indian Academy of Neurology 2015-10, Vol.18 (4), p.479-480
Main Authors: Incecik, Faruk, Herguner, Ozlem M, Besen, Seyda, Altunbasak, Sakir
Format: Article
Language:English
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Summary:Other mechanisms include inhibition of Zn2 + -associated negative gama-aminobutyric acid (GABA) modulation, high-voltage-gated N-type Ca2 + channel currents, and GABA release. There was no evidence of urinary and gastoinintestinal tract infection, and no evidence central nervous system involvement in our patient. [...]we thought the cause of his complaints due to LEV therapy. [...]we conclude that LEV may cause urinary and fecal incontinence, however these effects are reversible.
ISSN:0972-2327
1998-3549
DOI:10.4103/0972-2327.165476