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Burden of disease attributable to ambient fine particulate matter exposure in Taiwan

Background/Purpose There is compelling epidemiological evidence that links air pollution to increased risk of mortality from cardiopulmonary disease and lung cancer. We quantified the burden of mortality attributable to ambient fine particulate matter (PM2.5 ) among the Taiwanese population in 2014...

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Published in:Journal of the Formosan Medical Association 2017-01, Vol.116 (1), p.32-40
Main Authors: Lo, Wei-Cheng, Shie, Ruei-Hao, Chan, Chang-Chuan, Lin, Hsien-Ho
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description Background/Purpose There is compelling epidemiological evidence that links air pollution to increased risk of mortality from cardiopulmonary disease and lung cancer. We quantified the burden of mortality attributable to ambient fine particulate matter (PM2.5 ) among the Taiwanese population in 2014 at the national and subnational levels. Methods Subnational PM2.5 exposure levels were obtained from Taiwan Air Quality Monitoring Network. Relative risks were derived from a previously developed exposure-response model. Population attributable fraction for cause-specific mortality was estimated at the county level using the estimated ambient PM2.5 concentrations and the relative risk functions. Results In 2014, PM2.5 accounted for 6282 deaths [95% confidence interval (CI), 5716–6847], from ischemic heart disease (2244 deaths; 95% CI, 2015–2473), stroke (2140 deaths; 95% CI, 1760–2520), lung cancer (1252 deaths; 95% CI, 995–1509), and chronic obstructive pulmonary disease (645 deaths; 95% CI, 418–872). Nationally, the population attributable mortality fraction of PM2.5 for the four disease causes was 18.6% (95% CI, 16.9–20.3%). Substantial geographic variation in PM2.5 attributable mortality fraction was found; the percentage of deaths attributable to PM2.5 ranged from 8.7% in Hualian County to 21.8% in Yunlin County. In terms of absolute number of deaths, New Taipei and Kaohsiung cities had the largest number of deaths associated with PM2.5 (874 and 829 deaths, respectively) among all cities and counties. Conclusion Ambient PM2.5 pollution is a major mortality risk factor in Taiwan. Aggressive and multisectorial intervention strategies are urgently needed to bring down the impact of air pollution on environment and health.
doi_str_mv 10.1016/j.jfma.2015.12.007
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We quantified the burden of mortality attributable to ambient fine particulate matter (PM2.5 ) among the Taiwanese population in 2014 at the national and subnational levels. Methods Subnational PM2.5 exposure levels were obtained from Taiwan Air Quality Monitoring Network. Relative risks were derived from a previously developed exposure-response model. Population attributable fraction for cause-specific mortality was estimated at the county level using the estimated ambient PM2.5 concentrations and the relative risk functions. Results In 2014, PM2.5 accounted for 6282 deaths [95% confidence interval (CI), 5716–6847], from ischemic heart disease (2244 deaths; 95% CI, 2015–2473), stroke (2140 deaths; 95% CI, 1760–2520), lung cancer (1252 deaths; 95% CI, 995–1509), and chronic obstructive pulmonary disease (645 deaths; 95% CI, 418–872). Nationally, the population attributable mortality fraction of PM2.5 for the four disease causes was 18.6% (95% CI, 16.9–20.3%). Substantial geographic variation in PM2.5 attributable mortality fraction was found; the percentage of deaths attributable to PM2.5 ranged from 8.7% in Hualian County to 21.8% in Yunlin County. In terms of absolute number of deaths, New Taipei and Kaohsiung cities had the largest number of deaths associated with PM2.5 (874 and 829 deaths, respectively) among all cities and counties. Conclusion Ambient PM2.5 pollution is a major mortality risk factor in Taiwan. Aggressive and multisectorial intervention strategies are urgently needed to bring down the impact of air pollution on environment and health.</description><identifier>ISSN: 0929-6646</identifier><identifier>EISSN: 1876-0821</identifier><identifier>DOI: 10.1016/j.jfma.2015.12.007</identifier><identifier>PMID: 26874373</identifier><language>eng</language><publisher>Singapore: Elsevier B.V</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Air Pollution - adverse effects ; ambient fine particulate matter ; burden of disease ; Coronary Artery Disease - mortality ; Cost of Illness ; Demography ; Environmental Exposure - adverse effects ; Female ; Humans ; Internal Medicine ; Lung Neoplasms - mortality ; Male ; Middle Aged ; Myocardial Ischemia - mortality ; Particulate Matter - adverse effects ; Pulmonary Disease, Chronic Obstructive - mortality ; Risk Factors ; Stroke - mortality ; subnational analysis ; Taiwan</subject><ispartof>Journal of the Formosan Medical Association, 2017-01, Vol.116 (1), p.32-40</ispartof><rights>2016</rights><rights>Copyright © 2016. Published by Elsevier B.V.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c587t-a1cf92f9334bfffe246dae06c398adf2dd498700eb597641eb63186535c4ccd3</citedby><cites>FETCH-LOGICAL-c587t-a1cf92f9334bfffe246dae06c398adf2dd498700eb597641eb63186535c4ccd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26874373$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lo, Wei-Cheng</creatorcontrib><creatorcontrib>Shie, Ruei-Hao</creatorcontrib><creatorcontrib>Chan, Chang-Chuan</creatorcontrib><creatorcontrib>Lin, Hsien-Ho</creatorcontrib><title>Burden of disease attributable to ambient fine particulate matter exposure in Taiwan</title><title>Journal of the Formosan Medical Association</title><addtitle>J Formos Med Assoc</addtitle><description>Background/Purpose There is compelling epidemiological evidence that links air pollution to increased risk of mortality from cardiopulmonary disease and lung cancer. We quantified the burden of mortality attributable to ambient fine particulate matter (PM2.5 ) among the Taiwanese population in 2014 at the national and subnational levels. Methods Subnational PM2.5 exposure levels were obtained from Taiwan Air Quality Monitoring Network. Relative risks were derived from a previously developed exposure-response model. Population attributable fraction for cause-specific mortality was estimated at the county level using the estimated ambient PM2.5 concentrations and the relative risk functions. Results In 2014, PM2.5 accounted for 6282 deaths [95% confidence interval (CI), 5716–6847], from ischemic heart disease (2244 deaths; 95% CI, 2015–2473), stroke (2140 deaths; 95% CI, 1760–2520), lung cancer (1252 deaths; 95% CI, 995–1509), and chronic obstructive pulmonary disease (645 deaths; 95% CI, 418–872). Nationally, the population attributable mortality fraction of PM2.5 for the four disease causes was 18.6% (95% CI, 16.9–20.3%). Substantial geographic variation in PM2.5 attributable mortality fraction was found; the percentage of deaths attributable to PM2.5 ranged from 8.7% in Hualian County to 21.8% in Yunlin County. In terms of absolute number of deaths, New Taipei and Kaohsiung cities had the largest number of deaths associated with PM2.5 (874 and 829 deaths, respectively) among all cities and counties. Conclusion Ambient PM2.5 pollution is a major mortality risk factor in Taiwan. Aggressive and multisectorial intervention strategies are urgently needed to bring down the impact of air pollution on environment and health.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Air Pollution - adverse effects</subject><subject>ambient fine particulate matter</subject><subject>burden of disease</subject><subject>Coronary Artery Disease - mortality</subject><subject>Cost of Illness</subject><subject>Demography</subject><subject>Environmental Exposure - adverse effects</subject><subject>Female</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Lung Neoplasms - mortality</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myocardial Ischemia - mortality</subject><subject>Particulate Matter - adverse effects</subject><subject>Pulmonary Disease, Chronic Obstructive - mortality</subject><subject>Risk Factors</subject><subject>Stroke - mortality</subject><subject>subnational analysis</subject><subject>Taiwan</subject><issn>0929-6646</issn><issn>1876-0821</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNp9ks1u1DAUhS0EotPCC7BAXrJJ8F-cWEJIUFGoVIkFs7cc-xo5JPFgO4W-PZ5O6YIFK0vWOce-9zsIvaKkpYTKt1M7-cW0jNCupawlpH-CdnToZUMGRp-iHVFMNVIKeYbOc54IEVIp-RydMTn0gvd8h_Yft-RgxdFjFzKYDNiUksK4FTPOgEvEZhkDrAX7sAI-mFSC3WZTAC9VCQnD70PMWwIcVrw34ZdZX6Bn3swZXj6cF2h_9Wl_-aW5-fr5-vLDTWO7oS-NodYr5hXnYvTeAxPSGSDScjUY55lzQg09ITB2qpeCwig5HWTHOyusdfwCXZ9iXTSTPqSwmHSnown6_iKm7_r-tzNoJ3rKvXNk7Jjw3IxgeuEpMO6Vt6KrWW9OWYcUf26Qi15CtjDPZoW4ZU0HJmVHhBiqlJ2kNsWcE_jHpynRRzB60kcw-ghGU6YrmGp6_ZC_jQu4R8tfElXw7iSAurDbAElnW9duwYUEttSRwv_z3_9jt3NYgzXzD7iDPMUtrRWFpjpXg_52rMaxGbSrraCC8z_nBbSw</recordid><startdate>20170101</startdate><enddate>20170101</enddate><creator>Lo, Wei-Cheng</creator><creator>Shie, Ruei-Hao</creator><creator>Chan, Chang-Chuan</creator><creator>Lin, Hsien-Ho</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>DOA</scope></search><sort><creationdate>20170101</creationdate><title>Burden of disease attributable to ambient fine particulate matter exposure in Taiwan</title><author>Lo, Wei-Cheng ; Shie, Ruei-Hao ; Chan, Chang-Chuan ; Lin, Hsien-Ho</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c587t-a1cf92f9334bfffe246dae06c398adf2dd498700eb597641eb63186535c4ccd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Air Pollution - adverse effects</topic><topic>ambient fine particulate matter</topic><topic>burden of disease</topic><topic>Coronary Artery Disease - mortality</topic><topic>Cost of Illness</topic><topic>Demography</topic><topic>Environmental Exposure - adverse effects</topic><topic>Female</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Lung Neoplasms - mortality</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Myocardial Ischemia - mortality</topic><topic>Particulate Matter - adverse effects</topic><topic>Pulmonary Disease, Chronic Obstructive - mortality</topic><topic>Risk Factors</topic><topic>Stroke - mortality</topic><topic>subnational analysis</topic><topic>Taiwan</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lo, Wei-Cheng</creatorcontrib><creatorcontrib>Shie, Ruei-Hao</creatorcontrib><creatorcontrib>Chan, Chang-Chuan</creatorcontrib><creatorcontrib>Lin, Hsien-Ho</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Journal of the Formosan Medical Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lo, Wei-Cheng</au><au>Shie, Ruei-Hao</au><au>Chan, Chang-Chuan</au><au>Lin, Hsien-Ho</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Burden of disease attributable to ambient fine particulate matter exposure in Taiwan</atitle><jtitle>Journal of the Formosan Medical Association</jtitle><addtitle>J Formos Med Assoc</addtitle><date>2017-01-01</date><risdate>2017</risdate><volume>116</volume><issue>1</issue><spage>32</spage><epage>40</epage><pages>32-40</pages><issn>0929-6646</issn><eissn>1876-0821</eissn><abstract>Background/Purpose There is compelling epidemiological evidence that links air pollution to increased risk of mortality from cardiopulmonary disease and lung cancer. We quantified the burden of mortality attributable to ambient fine particulate matter (PM2.5 ) among the Taiwanese population in 2014 at the national and subnational levels. Methods Subnational PM2.5 exposure levels were obtained from Taiwan Air Quality Monitoring Network. Relative risks were derived from a previously developed exposure-response model. Population attributable fraction for cause-specific mortality was estimated at the county level using the estimated ambient PM2.5 concentrations and the relative risk functions. Results In 2014, PM2.5 accounted for 6282 deaths [95% confidence interval (CI), 5716–6847], from ischemic heart disease (2244 deaths; 95% CI, 2015–2473), stroke (2140 deaths; 95% CI, 1760–2520), lung cancer (1252 deaths; 95% CI, 995–1509), and chronic obstructive pulmonary disease (645 deaths; 95% CI, 418–872). Nationally, the population attributable mortality fraction of PM2.5 for the four disease causes was 18.6% (95% CI, 16.9–20.3%). Substantial geographic variation in PM2.5 attributable mortality fraction was found; the percentage of deaths attributable to PM2.5 ranged from 8.7% in Hualian County to 21.8% in Yunlin County. In terms of absolute number of deaths, New Taipei and Kaohsiung cities had the largest number of deaths associated with PM2.5 (874 and 829 deaths, respectively) among all cities and counties. Conclusion Ambient PM2.5 pollution is a major mortality risk factor in Taiwan. Aggressive and multisectorial intervention strategies are urgently needed to bring down the impact of air pollution on environment and health.</abstract><cop>Singapore</cop><pub>Elsevier B.V</pub><pmid>26874373</pmid><doi>10.1016/j.jfma.2015.12.007</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
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subjects Adult
Aged
Aged, 80 and over
Air Pollution - adverse effects
ambient fine particulate matter
burden of disease
Coronary Artery Disease - mortality
Cost of Illness
Demography
Environmental Exposure - adverse effects
Female
Humans
Internal Medicine
Lung Neoplasms - mortality
Male
Middle Aged
Myocardial Ischemia - mortality
Particulate Matter - adverse effects
Pulmonary Disease, Chronic Obstructive - mortality
Risk Factors
Stroke - mortality
subnational analysis
Taiwan
title Burden of disease attributable to ambient fine particulate matter exposure in Taiwan
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