Monte Carlo-based dose calculation for 32 P patch source for superficial brachytherapy applications

Skin cancer treatment involving 32 P source is an easy, less expensive method of treatment limited to small and superficial lesions of approximately 1 mm deep. Bhabha Atomic Research Centre (BARC) has indigenously developed 32 P nafion-based patch source (1 cm Χ 1 cm) for treating skin cancer. For t...

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Bibliographic Details
Published in:Journal of medical physics 2015-01, Vol.40 (1), p.13-17
Main Authors: Sahoo, Sridhar, Palani, Selvam, Saxena, S, Babu, D A R, Dash, A
Format: Article
Language:English
Subjects:
32 P patch
brachytherapy
dosimetry
nafion
skin cancer
Brachytherapy
Chemotherapy
Radiation therapy
Skin cancer
Studies
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Summary:Skin cancer treatment involving 32 P source is an easy, less expensive method of treatment limited to small and superficial lesions of approximately 1 mm deep. Bhabha Atomic Research Centre (BARC) has indigenously developed 32 P nafion-based patch source (1 cm Χ 1 cm) for treating skin cancer. For this source, the values of dose per unit activity at different depths including dose profiles in water are calculated using the EGSnrc-based Monte Carlo code system. For an initial activity of 1 Bq distributed in 1 cm 2 surface area of the source, the calculated central axis depth dose values are 3.62 Χ 10 -10 GyBq -1 and 8.41 Χ 10 -11 GyBq -1 at 0.0125 and 1 mm depths in water, respectively. Hence, the treatment time calculated for delivering therapeutic dose of 30 Gy at 1 mm depth along the central axis of the source involving 37 MBq activity is about 2.7 hrs.
ISSN:0971-6203
1998-3913
DOI:10.4103/0971-6203.152232