The uric acid/HDL-C ratio may predict significant coronary stenosis in moderate left main coronary artery lesions: an intravascular ultrasonography study

• Published in: Lipids in health and disease 2024-07, Vol.23 (1), p.233-10, Article 233
• Main Authors: Demir, Ömer Furkan, Arslan, Abdulsamet, Kınık, Mustafa, Şensoy, Barış, Demir, Günseli
• Format: Article
• Language: English
• Subjects: Aged; Cholesterol, HDL - blood; Coronary artery disease; Coronary Artery Disease - blood; Coronary Artery Disease - diagnostic imaging; Coronary Artery Disease - pathology; Coronary heart disease; Coronary Stenosis - blood; Coronary Stenosis - diagnostic imaging; Coronary Stenosis - pathology; Coronary Vessels - diagnostic imaging; Coronary Vessels - pathology; Female; High-density lipoprotein cholesterol; Humans; Intravascular ultrasound; Left main coronary artery; Male; Medical research; Medicine, Experimental; Middle Aged; Plaque, Atherosclerotic - diagnostic imaging; ROC Curve; Severity of Illness Index; Stenosis; Ultrasonography, Interventional; Ultrasound imaging; Uric acid; Uric Acid - blood
• ISSN: 1476-511X; 1476-511X
• DOI: 10.1186/s12944-024-02193-y

There may be severe difficulties in determining the severity of LMCA (left main coronary artery) lesions. The use of intravascular ultrasound (IVUS) facilitates decisions about lesion severity in these patients. The aim of this study was to investigate the relationship between the UHR (uric acid to HDL-C ratio) and lesion severity in patients who underwent LMCA IVUS. This study included 205 patients with ICS (intermediate coronary stenosis) in the LMCA who underwent IVUS. In the IVUS measurements of these patients, the plaque burden (PB) and the minimal lumen area (MLA) showing lesion severity were measured. The patients were separated into two groups according to plaque burden (