A Star Polyamine-Based Nanocarrier Delivery System for Enhanced Avermectin Contact and Stomach Toxicity against Green Peach Aphids

• Published in: Nanomaterials (Basel, Switzerland) Switzerland), 2022-04, Vol.12 (9), p.1445
• Main Authors: Yang, Yanxiao, Jiang, Qinhong, Peng, Min, Zhou, Ziyi, Du, Xiangge, Yin, Meizhen, Shen, Jie, Yan, Shuo
• Format: Article
• Language: English
• Subjects: Agricultural land; Agricultural production; Aqueous solutions; Avermectin; Biocompatibility; Biological activity; Carbonyl compounds; Carbonyl groups; Carbonyls; Contact angle; Efficiency; Epicuticle; Ethanol; Hydrogen bonds; Hydroxyl groups; Insecticide resistance; Insects; Mass ratios; Morphology; nanocarrier; nanopesticide; Particle size; Pathogens; Permeability; pest management; pesticide nanometerization; Pesticide toxicity; Pesticides; Pests; Plant resistance; Polyamines; Polymerization; Self-assembly; star polyamine; Stomach; Toxicity; Van der Waals forces
• ISSN: 2079-4991; 2079-4991
• DOI: 10.3390/nano12091445

The unscientific application of synthesized/botanical pesticides has not only brought the resistance of plant pathogens and pests, but also led to serious environmental pollution. In recent years, various nano-delivery systems have been used for the development of environmental-friendly pesticides with improved efficacy. Herein, the current study constructed an efficient avermectin B1a (AVM) nano-delivery system based on a star polyamine (SPc) and focused on the characterization and bioactivity of SPc-loaded AVM at various mass ratios. The hydroxyl groups of AVM could assemble with carbonyl groups of SPc through hydrogen bond and van der Waals forces, and the self-assembly of AVM and SPc formed nearly spherical particles of AVM/SPc complex with nanoscale size. The contact angle of SPc-loaded AVM decreased with the increasing mass ratio of SPc, revealing the easier distribution and spreading of the AVM/SPc complex. Furthermore, the stomach and contact toxicity of AVM/SPc complex also increased along with the increasing SPc mass ratio, which could be attributed to the enhanced systemic transportation in plants, enlarged contact area to insect pests and stronger permeability across the insect cuticle. The current study provides an efficient nano-delivery system for increasing stomach and contact toxicity of pesticides with wide applications in the agricultural field.