In Silico Discovery of Mitosis Regulation Networks Associated with Early Distant Metastases in Estrogen Receptor Positive Breast Cancers

The aim of this study was to perform comparative analysis of multiple public datasets of gene expression in order to identify common genes as potential prognostic biomarkers. Additionally, the study sought to identify biological processes and pathways that are most significantly associated with earl...

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Bibliographic Details
Published in:Cancer informatics 2013-01, Vol.2013 (12), p.31-51
Main Authors: Gusev, Yuriy, Riggins, Rebecca B., Bhuvaneshwar, Krithika, Gauba, Robinder, Sheahan, Laura, Clarke, Robert, Madhavan, Subha
Format: Article
Language:English
Subjects:
Analysis
Breast cancer
Cancer
Care and treatment
Discovery and exploration
Estrogen
Gene expression
Genes
Metastasis
MicroRNA
Original Research
Phenols
Vinca
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Summary:The aim of this study was to perform comparative analysis of multiple public datasets of gene expression in order to identify common genes as potential prognostic biomarkers. Additionally, the study sought to identify biological processes and pathways that are most significantly associated with early distant metastases (
ISSN:1176-9351
1176-9351
DOI:10.4137/CIN.S10329