T.H.R.O.B.V.S. Score – A Comprehensive Model to Predict the Surgical Complexity of Renal Cell Carcinoma With Tumor Thrombus

BackgroundTo propose a quantitative model for predicting the surgical complexity of patients with renal cell carcinoma (RCC) and venous tumor thrombus (VTT). MethodThe clinical data of 226 cases of RCC with VTT in Peking University Third Hospital from January 2014 to August 2020 were retrospectively...

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Bibliographic Details
Published in:Frontiers in oncology 2022-06, Vol.12, p.900550-900550
Main Authors: Wang, Kai, Liu, Zhuo, Hong, Peng, Qin, Yan-chun, Zhao, Xun, Zhang, Hong-xian, Liu, Cheng, Ge, Li-yuan, Ma, Lu-lin
Format: Article
Language:English
Subjects:
nephrectomy
Oncology
prediction model
renal cell carcinoma
surgical complexity
thrombectomy
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Summary:BackgroundTo propose a quantitative model for predicting the surgical complexity of patients with renal cell carcinoma (RCC) and venous tumor thrombus (VTT). MethodThe clinical data of 226 cases of RCC with VTT in Peking University Third Hospital from January 2014 to August 2020 were retrospectively analyzed. Seven indicators were selected to establish the T.H.R.O.B.V.S. system, including alkaline phosphatase, tumor thrombus height, maximum tumor diameter, obesity, bland thrombus, vascular wall invasion, and side. Each indicator was assigned with 0, (1), and 2 points, and the total scores of 0~2, 3~5, and ≥6 were set as the low-, middle-, and high-risk groups, respectively. The surgical complexity was compared and validated among groups. ResultsAs the risk increased, the proportion of open surgery significantly increased (P
ISSN:2234-943X
2234-943X
DOI:10.3389/fonc.2022.900550