High-resolution functional photoacoustic monitoring of vascular dynamics in human fingers

Functional imaging of microvascular dynamics in extremities delivers intuitive information for early detection, diagnosis, and prognosis of vascular diseases. High-resolution and high-speed photoacoustic microscopy (PAM) visualizes and measures multiparametric information of microvessel networks in...

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Bibliographic Details
Published in:Photoacoustics (Munich) 2021-09, Vol.23, p.100282-100282, Article 100282
Main Authors: Ahn, Joongho, Kim, Jin Young, Choi, Wonseok, Kim, Chulhong
Format: Article
Language:English
Subjects:
Blood vessel
Digital vasculature
Hemodynamics
Oxygen saturation
Perfusion
Photoacoustic microscopy
Pulsation
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Summary:Functional imaging of microvascular dynamics in extremities delivers intuitive information for early detection, diagnosis, and prognosis of vascular diseases. High-resolution and high-speed photoacoustic microscopy (PAM) visualizes and measures multiparametric information of microvessel networks in vivo such as morphology, flow, oxygen saturation, and metabolic rate. Here, we demonstrate high-resolution photoacoustic monitoring of vascular dynamics in human fingers. We photoacoustically monitored the position displacement of blood vessels associated with arterial pulsation in human fingers. Then, during and after arterial occlusion, we photoacoustically quantified oxygen consumption and blood perfusion in the fingertips. The results demonstrate that high-resolution functional PAM could be a vital tool in peripheral vascular examination for measuring heart rate, oxygen consumption, and/or blood perfusion.
ISSN:2213-5979
2213-5979
DOI:10.1016/j.pacs.2021.100282