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Identification of subgroups of patients with tension type headache with higher widespread pressure pain hyperalgesia
Background Identification of subgroups of patients with different levels of sensitization and clinical features can help to identify groups at risk and the development of better therapeutic strategies. The aim of this study was to identify subgroups of patients with tension type headache (TTH) with...
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| Published in: | Journal of headache and pain 2017-12, Vol.18 (1), p.43-43, Article 43 |
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| container_end_page | 43 |
| container_issue | 1 |
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| container_title | Journal of headache and pain |
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| creator | Fernández-de-las-Peñas, César Benito-González, Elena Palacios-Ceña, María Wang, Kelun Castaldo, Matteo Arendt-Nielsen, Lars |
| description | Background
Identification of subgroups of patients with different levels of sensitization and clinical features can help to identify groups at risk and the development of better therapeutic strategies. The aim of this study was to identify subgroups of patients with tension type headache (TTH) with different levels of sensitization, clinical pain features, and psychological outcomes.
Methods
A total of 197 individuals with TTH participated. Headache intensity, frequency, and duration and medication intake were collected with a 4-weeks diary. Pressure pain thresholds were assessed bilaterally over the temporalis muscle, C5-C6 joint, second metacarpal and tibialis anterior muscle to determine widespread pressure pain hyperalgesia. The Hospital Anxiety and Depression Scale assessed anxiety and depression. The State-Trait Anxiety Inventory evaluated the state and trait levels of anxiety. The Headache Disability Inventory evaluated the burden of headache. Health-related quality of life was determined with the SF-36 questionnaire. Groups were considered as positive (three or more criteria) or negative (less than three criteria) on a clinical prediction rule: headache duration |
| doi_str_mv | 10.1186/s10194-017-0751-0 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_d64cdece40674c19aeeebb9664b4453a</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_d64cdece40674c19aeeebb9664b4453a</doaj_id><sourcerecordid>4321603391</sourcerecordid><originalsourceid>FETCH-LOGICAL-c569t-11cd1958bd04e3127e0d0aa7fe4e06778da93790ca681f1a1d05aba4f3462ef03</originalsourceid><addsrcrecordid>eNqNkk2L1TAUhosozjj6A9xIwY2bjjltPjeCDOpcGHCj65Amp20u9zY1aR3m35va8TIjCG6aNOfJ05z0LYrXQC4BJH-fgICiFQFREcGgIk-Kc4BaVXUjxNPTnKuz4kVKe0Jq0kj2vDirJSVAlTwv5p3Dcfadt2b2YSxDV6al7WNYprS-THk5A6m89fNQzjimlZrvJiwHNM7YAbfS4PsBY547TFPMpTI_U1oiZocfyyFviebQY_LmZfGsM4eEr-7Hi-L750_frq6rm69fdlcfbyrLuJorAOtAMdk6QrGBWiBxxBjRIUXChZDOqEYoYg2X0IEBR5hpDe0aymvsSHNR7DavC2avp-iPJt7pYLz-vRBir02cvT2gdpxahxZpFlMLyiBi2yrOaUspa0x2fdhc09Ie0dl8KbmdR9LHldEPug8_NWuk5Jxnwbt7QQw_FkyzPvpk8XAwI4YlaZBKNFIxUP-BSkEYlWxt8e1f6D4sccy3ulK8rhkwminYKBtDShG707mB6DVKeouSzlHSa5T0an7zsOHTjj_ZyUC9Afl_-7HH-ODT_7T-AsZT1uA</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1886225154</pqid></control><display><type>article</type><title>Identification of subgroups of patients with tension type headache with higher widespread pressure pain hyperalgesia</title><source>Springer Nature - SpringerLink Journals - Fully Open Access</source><source>Publicly Available Content (ProQuest)</source><source>PubMed Central</source><creator>Fernández-de-las-Peñas, César ; Benito-González, Elena ; Palacios-Ceña, María ; Wang, Kelun ; Castaldo, Matteo ; Arendt-Nielsen, Lars</creator><creatorcontrib>Fernández-de-las-Peñas, César ; Benito-González, Elena ; Palacios-Ceña, María ; Wang, Kelun ; Castaldo, Matteo ; Arendt-Nielsen, Lars</creatorcontrib><description>Background
Identification of subgroups of patients with different levels of sensitization and clinical features can help to identify groups at risk and the development of better therapeutic strategies. The aim of this study was to identify subgroups of patients with tension type headache (TTH) with different levels of sensitization, clinical pain features, and psychological outcomes.
Methods
A total of 197 individuals with TTH participated. Headache intensity, frequency, and duration and medication intake were collected with a 4-weeks diary. Pressure pain thresholds were assessed bilaterally over the temporalis muscle, C5-C6 joint, second metacarpal and tibialis anterior muscle to determine widespread pressure pain hyperalgesia. The Hospital Anxiety and Depression Scale assessed anxiety and depression. The State-Trait Anxiety Inventory evaluated the state and trait levels of anxiety. The Headache Disability Inventory evaluated the burden of headache. Health-related quality of life was determined with the SF-36 questionnaire. Groups were considered as positive (three or more criteria) or negative (less than three criteria) on a clinical prediction rule: headache duration <8.5 h/day; headache frequency <5.5 days/week; bodily pain <47 and vitality <47.5.
Results
The ANCOVA revealed that subjects in group 1 (positive rule,
n
= 89) exhibited longer headache history, shorter headache duration, lower headache frequency, higher widespread pressure hyperalgesia, higher anxiety trait levels, and lower quality of life (all,
P
< 0.01) than those subjects within group 2 (negative rule,
n
= 108). Differences were similar between men and women.
Conclusions
This study identified a subgroup of patients with TTH with higher sensitization, higher chronicity of headaches and worse quality of life but lower frequency and duration of headache episodes. This subgroup of individuals with TTH may need particular attention and specific therapeutic programs for avoiding potential chronification.</description><identifier>ISSN: 1129-2369</identifier><identifier>EISSN: 1129-2377</identifier><identifier>DOI: 10.1186/s10194-017-0751-0</identifier><identifier>PMID: 28401498</identifier><identifier>CODEN: JHPOAT</identifier><language>eng</language><publisher>Milan: Springer Milan</publisher><subject>Adult ; Anxiety - physiopathology ; Cross-Sectional Studies ; Epidemiology ; Female ; Groups ; Headaches ; Humans ; Hyperalgesia - physiopathology ; Internal Medicine ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Neurology ; Pain ; Pain Medicine ; Pain Threshold - physiology ; Quality of Life ; Research Article ; Sensitization ; Tension type headache ; Tension-Type Headache - classification ; Tension-Type Headache - physiopathology ; Tension-Type Headache - psychology</subject><ispartof>Journal of headache and pain, 2017-12, Vol.18 (1), p.43-43, Article 43</ispartof><rights>The Author(s). 2017</rights><rights>The Journal of Headache and Pain is a copyright of Springer, 2017.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c569t-11cd1958bd04e3127e0d0aa7fe4e06778da93790ca681f1a1d05aba4f3462ef03</citedby><cites>FETCH-LOGICAL-c569t-11cd1958bd04e3127e0d0aa7fe4e06778da93790ca681f1a1d05aba4f3462ef03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1886225154/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1886225154?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25752,27923,27924,37011,37012,44589,53790,53792,74897</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28401498$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fernández-de-las-Peñas, César</creatorcontrib><creatorcontrib>Benito-González, Elena</creatorcontrib><creatorcontrib>Palacios-Ceña, María</creatorcontrib><creatorcontrib>Wang, Kelun</creatorcontrib><creatorcontrib>Castaldo, Matteo</creatorcontrib><creatorcontrib>Arendt-Nielsen, Lars</creatorcontrib><title>Identification of subgroups of patients with tension type headache with higher widespread pressure pain hyperalgesia</title><title>Journal of headache and pain</title><addtitle>J Headache Pain</addtitle><addtitle>J Headache Pain</addtitle><description>Background
Identification of subgroups of patients with different levels of sensitization and clinical features can help to identify groups at risk and the development of better therapeutic strategies. The aim of this study was to identify subgroups of patients with tension type headache (TTH) with different levels of sensitization, clinical pain features, and psychological outcomes.
Methods
A total of 197 individuals with TTH participated. Headache intensity, frequency, and duration and medication intake were collected with a 4-weeks diary. Pressure pain thresholds were assessed bilaterally over the temporalis muscle, C5-C6 joint, second metacarpal and tibialis anterior muscle to determine widespread pressure pain hyperalgesia. The Hospital Anxiety and Depression Scale assessed anxiety and depression. The State-Trait Anxiety Inventory evaluated the state and trait levels of anxiety. The Headache Disability Inventory evaluated the burden of headache. Health-related quality of life was determined with the SF-36 questionnaire. Groups were considered as positive (three or more criteria) or negative (less than three criteria) on a clinical prediction rule: headache duration <8.5 h/day; headache frequency <5.5 days/week; bodily pain <47 and vitality <47.5.
Results
The ANCOVA revealed that subjects in group 1 (positive rule,
n
= 89) exhibited longer headache history, shorter headache duration, lower headache frequency, higher widespread pressure hyperalgesia, higher anxiety trait levels, and lower quality of life (all,
P
< 0.01) than those subjects within group 2 (negative rule,
n
= 108). Differences were similar between men and women.
Conclusions
This study identified a subgroup of patients with TTH with higher sensitization, higher chronicity of headaches and worse quality of life but lower frequency and duration of headache episodes. This subgroup of individuals with TTH may need particular attention and specific therapeutic programs for avoiding potential chronification.</description><subject>Adult</subject><subject>Anxiety - physiopathology</subject><subject>Cross-Sectional Studies</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Groups</subject><subject>Headaches</subject><subject>Humans</subject><subject>Hyperalgesia - physiopathology</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Neurology</subject><subject>Pain</subject><subject>Pain Medicine</subject><subject>Pain Threshold - physiology</subject><subject>Quality of Life</subject><subject>Research Article</subject><subject>Sensitization</subject><subject>Tension type headache</subject><subject>Tension-Type Headache - classification</subject><subject>Tension-Type Headache - physiopathology</subject><subject>Tension-Type Headache - psychology</subject><issn>1129-2369</issn><issn>1129-2377</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqNkk2L1TAUhosozjj6A9xIwY2bjjltPjeCDOpcGHCj65Amp20u9zY1aR3m35va8TIjCG6aNOfJ05z0LYrXQC4BJH-fgICiFQFREcGgIk-Kc4BaVXUjxNPTnKuz4kVKe0Jq0kj2vDirJSVAlTwv5p3Dcfadt2b2YSxDV6al7WNYprS-THk5A6m89fNQzjimlZrvJiwHNM7YAbfS4PsBY547TFPMpTI_U1oiZocfyyFviebQY_LmZfGsM4eEr-7Hi-L750_frq6rm69fdlcfbyrLuJorAOtAMdk6QrGBWiBxxBjRIUXChZDOqEYoYg2X0IEBR5hpDe0aymvsSHNR7DavC2avp-iPJt7pYLz-vRBir02cvT2gdpxahxZpFlMLyiBi2yrOaUspa0x2fdhc09Ie0dl8KbmdR9LHldEPug8_NWuk5Jxnwbt7QQw_FkyzPvpk8XAwI4YlaZBKNFIxUP-BSkEYlWxt8e1f6D4sccy3ulK8rhkwminYKBtDShG707mB6DVKeouSzlHSa5T0an7zsOHTjj_ZyUC9Afl_-7HH-ODT_7T-AsZT1uA</recordid><startdate>20171201</startdate><enddate>20171201</enddate><creator>Fernández-de-las-Peñas, César</creator><creator>Benito-González, Elena</creator><creator>Palacios-Ceña, María</creator><creator>Wang, Kelun</creator><creator>Castaldo, Matteo</creator><creator>Arendt-Nielsen, Lars</creator><general>Springer Milan</general><general>Springer Nature B.V</general><general>BMC</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20171201</creationdate><title>Identification of subgroups of patients with tension type headache with higher widespread pressure pain hyperalgesia</title><author>Fernández-de-las-Peñas, César ; Benito-González, Elena ; Palacios-Ceña, María ; Wang, Kelun ; Castaldo, Matteo ; Arendt-Nielsen, Lars</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c569t-11cd1958bd04e3127e0d0aa7fe4e06778da93790ca681f1a1d05aba4f3462ef03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Anxiety - physiopathology</topic><topic>Cross-Sectional Studies</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Groups</topic><topic>Headaches</topic><topic>Humans</topic><topic>Hyperalgesia - physiopathology</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Neurology</topic><topic>Pain</topic><topic>Pain Medicine</topic><topic>Pain Threshold - physiology</topic><topic>Quality of Life</topic><topic>Research Article</topic><topic>Sensitization</topic><topic>Tension type headache</topic><topic>Tension-Type Headache - classification</topic><topic>Tension-Type Headache - physiopathology</topic><topic>Tension-Type Headache - psychology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fernández-de-las-Peñas, César</creatorcontrib><creatorcontrib>Benito-González, Elena</creatorcontrib><creatorcontrib>Palacios-Ceña, María</creatorcontrib><creatorcontrib>Wang, Kelun</creatorcontrib><creatorcontrib>Castaldo, Matteo</creatorcontrib><creatorcontrib>Arendt-Nielsen, Lars</creatorcontrib><collection>SpringerOpen (Open Access)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Psychology Database (ProQuest)</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Journal of headache and pain</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fernández-de-las-Peñas, César</au><au>Benito-González, Elena</au><au>Palacios-Ceña, María</au><au>Wang, Kelun</au><au>Castaldo, Matteo</au><au>Arendt-Nielsen, Lars</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Identification of subgroups of patients with tension type headache with higher widespread pressure pain hyperalgesia</atitle><jtitle>Journal of headache and pain</jtitle><stitle>J Headache Pain</stitle><addtitle>J Headache Pain</addtitle><date>2017-12-01</date><risdate>2017</risdate><volume>18</volume><issue>1</issue><spage>43</spage><epage>43</epage><pages>43-43</pages><artnum>43</artnum><issn>1129-2369</issn><eissn>1129-2377</eissn><coden>JHPOAT</coden><abstract>Background
Identification of subgroups of patients with different levels of sensitization and clinical features can help to identify groups at risk and the development of better therapeutic strategies. The aim of this study was to identify subgroups of patients with tension type headache (TTH) with different levels of sensitization, clinical pain features, and psychological outcomes.
Methods
A total of 197 individuals with TTH participated. Headache intensity, frequency, and duration and medication intake were collected with a 4-weeks diary. Pressure pain thresholds were assessed bilaterally over the temporalis muscle, C5-C6 joint, second metacarpal and tibialis anterior muscle to determine widespread pressure pain hyperalgesia. The Hospital Anxiety and Depression Scale assessed anxiety and depression. The State-Trait Anxiety Inventory evaluated the state and trait levels of anxiety. The Headache Disability Inventory evaluated the burden of headache. Health-related quality of life was determined with the SF-36 questionnaire. Groups were considered as positive (three or more criteria) or negative (less than three criteria) on a clinical prediction rule: headache duration <8.5 h/day; headache frequency <5.5 days/week; bodily pain <47 and vitality <47.5.
Results
The ANCOVA revealed that subjects in group 1 (positive rule,
n
= 89) exhibited longer headache history, shorter headache duration, lower headache frequency, higher widespread pressure hyperalgesia, higher anxiety trait levels, and lower quality of life (all,
P
< 0.01) than those subjects within group 2 (negative rule,
n
= 108). Differences were similar between men and women.
Conclusions
This study identified a subgroup of patients with TTH with higher sensitization, higher chronicity of headaches and worse quality of life but lower frequency and duration of headache episodes. This subgroup of individuals with TTH may need particular attention and specific therapeutic programs for avoiding potential chronification.</abstract><cop>Milan</cop><pub>Springer Milan</pub><pmid>28401498</pmid><doi>10.1186/s10194-017-0751-0</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1129-2369 |
| ispartof | Journal of headache and pain, 2017-12, Vol.18 (1), p.43-43, Article 43 |
| issn | 1129-2369 1129-2377 |
| language | eng |
| recordid | cdi_doaj_primary_oai_doaj_org_article_d64cdece40674c19aeeebb9664b4453a |
| source | Springer Nature - SpringerLink Journals - Fully Open Access; Publicly Available Content (ProQuest); PubMed Central |
| subjects | Adult Anxiety - physiopathology Cross-Sectional Studies Epidemiology Female Groups Headaches Humans Hyperalgesia - physiopathology Internal Medicine Male Medicine Medicine & Public Health Middle Aged Neurology Pain Pain Medicine Pain Threshold - physiology Quality of Life Research Article Sensitization Tension type headache Tension-Type Headache - classification Tension-Type Headache - physiopathology Tension-Type Headache - psychology |
| title | Identification of subgroups of patients with tension type headache with higher widespread pressure pain hyperalgesia |
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