Novel HIV-1 recombinant forms in antenatal cohort, Montreal, Quebec, Canada

Near full-length genomes of 4 unclassified HIV-1 variants infecting patients enrolled in an antenatal cohort in Canada were obtained by sequencing. All 4 variants showed original recombination profiles, including A1/A2/J, A1/D, and A1/G/J/CRF11_cpx structures. Identification of these variants highli...

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Bibliographic Details
Published in:Emerging infectious diseases 2011-02, Vol.17 (2), p.271-274
Main Authors: Quesnel-Vallières, Mathieu, Kouzayha, Iman, Tran, Evelyne, Barry, Issatou, Lasgi, Charlène, Merindol, Natacha, Monteil, Vanessa, Ransy, Doris G, Boucher, Marc, Lapointe, Normand, Soudeyns, Hugo
Format: Article
Language:English
Subjects:
AIDS
Canada
Canada - epidemiology
Care and treatment
Cohort Studies
Dispatch
Female
Genetic aspects
genetic recombination
Genome, Viral
HIV (Viruses)
HIV infection
HIV Infections - diagnosis
HIV Infections - epidemiology
HIV Infections - virology
HIV-1
HIV-1 - classification
HIV-1 - genetics
HIV-1 - isolation & purification
Humans
Infection
Phylogeny
Pregnancy
Pregnancy Complications, Infectious - diagnosis
Pregnancy Complications, Infectious - epidemiology
Pregnancy Complications, Infectious - virology
Prenatal Diagnosis
Prevalence
Quebec - epidemiology
Recombination, Genetic
Sequence Analysis, DNA
viral subtypes
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Description
Summary:Near full-length genomes of 4 unclassified HIV-1 variants infecting patients enrolled in an antenatal cohort in Canada were obtained by sequencing. All 4 variants showed original recombination profiles, including A1/A2/J, A1/D, and A1/G/J/CRF11_cpx structures. Identification of these variants highlights the growing prevalence of unique recombinant forms of HIV-1 in North America.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid1702.100629