Computerized electrocardiography in healthy conscious guinea pigs (Cavia porcellus)

The purpose of this study is to evaluate healthy conscious guinea pigs as a model for electrophysiology assessment and to describe normal electrocardiographic patterns in controlled laboratory environment, establishing the best QT formula for this method. Electrocardiographic recordings of fifty adu...

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Bibliographic Details
Published in:Pesquisa Veterinária Brasileira 2016-12, Vol.36 (12), p.1203-1208
Main Authors: Botelho, Ana F.M., Oliveira, Maira S. de, Soto-Blanco, Benito, Melo, Marília M.
Format: Article
Language:English
Subjects:
computerized ECG
conscious
electrocardiogram
Guinea pigs
VETERINARY SCIENCES
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Summary:The purpose of this study is to evaluate healthy conscious guinea pigs as a model for electrophysiology assessment and to describe normal electrocardiographic patterns in controlled laboratory environment, establishing the best QT formula for this method. Electrocardiographic recordings of fifty adult conscious guinea pigs were obtained using a computerized electrocardiography. The electrocardiographic measurements of three different tracings were analyzed. The results obtained established normal mean and range values for the parameters: heart rate, waves and intervals of P-QRS-T deflections, as well as the mean cardiac axis. Groups were separated by body weight: group 1 gathered animals with 500-699g and group 2 with animals 700-900g. No differences were found when measurements were compared between groups, showing no significant difference between weight/body sizes to the electrocardiographic parameters (P
ISSN:0100-736X
1678-5150
0100-736X
DOI:10.1590/s0100-736x2016001200011