Mycosporine-Like Amino Acids from Red Macroalgae: UV-Photoprotectors with Potential Cosmeceutical Applications

• Published in: Applied sciences 2021-06, Vol.11 (11), p.5112
• Main Authors: Vega, Julia, Schneider, Geniane, Moreira, Bruna R., Herrera, Carolina, Bonomi-Barufi, José, Figueroa, Félix L.
• Format: Article
• Language: English
• Subjects: Algae; Amino acids; Antioxidants; Biomolecules; Biosynthesis; cosmeceutic; Cosmeceuticals; Environmental factors; extractions; Free radicals; High performance liquid chromatography; integrated multitrophic aquaculture (IMTA); Liquid chromatography; Mass spectrometry; Mass spectroscopy; Mycosporine-like amino acids; mycosporine-like amino acids (MAAs); NMR; Nuclear magnetic resonance; Porphyra; purification; Radiation; Solar radiation; Ultraviolet radiation
• ISSN: 2076-3417; 2076-3417
• DOI: 10.3390/app11115112

Macroalgae belong to a diverse group of organisms that could be exploited for biomolecule application. Among the biocompounds found in this group, mycosporine-like amino acids (MAAs) are highlighted mainly due to their photoprotection, antioxidant properties, and high photo and thermo-stability, which are attractive characteristics for the development of cosmeceutical products. Therefore, here we revise published data about MAAs, including their biosynthesis, biomass production, extraction, characterization, identification, purification, and bioactivities. MAAs can be found in many algae species, but the highest concentrations are found in red macroalgae, mainly in the order Bangiales, as Porphyra spp. In addition to the species, the content of MAAs can vary depending on environmental factors, of which solar radiation and nitrogen availability are the most influential. MAAs can confer photoprotection due to their capacity to absorb ultraviolet radiation or reduce the impact of free radicals on cells, among other properties. To extract these compounds, different approaches can be used. The efficiency of these methods can be evaluated with characterization and identification using high performance liquid chromatography (HPLC), associated with other apparatus such as mass spectrometry (MS) and nuclear magnetic resonance (NMR). Therefore, the data presented in this review allow a broad comprehension of MAAs and show perspectives for their inclusion in cosmeceutical products.