Value of contrast-enhanced CT texture analysis in predicting IDH mutation status of intrahepatic cholangiocarcinoma

To explore the value of contrast-enhanced CT texture analysis in predicting isocitrate dehydrogenase ( IDH ) mutation status of intrahepatic cholangiocarcinomas (ICCs). Institutional review board approved this study. Contrast-enhanced CT images of 138 ICC patients (21 with IDH mutation and 117 witho...

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Bibliographic Details
Published in:Scientific reports 2021-03, Vol.11 (1), p.6933-6933, Article 6933
Main Authors: Zhu, Yong, Mao, Yingfan, Chen, Jun, Qiu, Yudong, Guan, Yue, Wang, Zhongqiu, He, Jian
Format: Article
Language:English
Subjects:
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639/705
692/499
Cholangiocarcinoma
Humanities and Social Sciences
Isocitrate dehydrogenase
multidisciplinary
Mutation
Science
Science (multidisciplinary)
Support vector machines
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Summary:To explore the value of contrast-enhanced CT texture analysis in predicting isocitrate dehydrogenase ( IDH ) mutation status of intrahepatic cholangiocarcinomas (ICCs). Institutional review board approved this study. Contrast-enhanced CT images of 138 ICC patients (21 with IDH mutation and 117 without IDH mutation) were retrospectively reviewed. Texture analysis was performed for each lesion and compared between ICCs with and without IDH mutation. All textural features in each phase and combinations of textural features (p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-021-86497-4