Menstrual migraine and pathophysiology: estrogens and other factors

Abstract Migraine is a common disabling brain disorder. Its pathophysiology is now being better understood. It was considered a disorder of blood vessels; new pieces of evidence have led to the conclusion that migraine represents a high interaction between the peripheral and central nervous systems,...

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Bibliographic Details
Published in:Revista chilena de obstetricia y ginecología 2024-10, Vol.89 (5), p.339-346
Main Author: Núñez-Troconis, José
Format: Article
Language:eng ; por
Subjects:
Headache. Migraine disorders. Menstrual migraine. Pathophysiology. Estrogen
OBSTETRICS & GYNECOLOGY
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Summary:Abstract Migraine is a common disabling brain disorder. Its pathophysiology is now being better understood. It was considered a disorder of blood vessels; new pieces of evidence have led to the conclusion that migraine represents a high interaction between the peripheral and central nervous systems, with the trigeminovascular system and the cerebral cortex among the main players. Menstrual migraine (MM) is a condition in females, where headaches are linked with menstruation. Hormonal fluctuations could have a key role in migraine pathogenesis, as several women experience that their migraine attacks correlate with their menstrual cycle. Estrogen withdrawal appears to have a significant role in migraine associated with menstrual cycles, even though its pathophysiology is not well known. This article highlights some portions of what is known about the pathophysiology of MM and aims to provide a better understanding of MM in women with this condition.
ISSN:0717-7526
0717-7526
DOI:10.24875/rechog.24000022