Clinical and histological comparison of platelet-rich fibrin versus non-eugenol periodontal dressing in the treatment of gingival hyperpigmentation

Background: The platelet-rich fibrin (PRF) has proven an immense role in angiogenesis and epithelization in a wound healing process. The present study aims to ascertain PRF's beneficial role in wound healing after depigmentation surgery. Materials and Methods: A total of 12 systemically healthy...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Indian Society of Periodontology 2019-07, Vol.23 (4), p.345-350
Main Authors: Dahiya, Ritu, Blaggana, Anshu, Panwar, Vinod, Kumar, Shubham, Kathuria, Abhinav, Malik, Srijna
Format: Article
Language:English
Subjects:
Angiogenesis
Biopsy
Cell division
Comparative analysis
Eugenol
Fibrin
Gingival hyperpigmentation
Hyperpigmentation
Inflammation
Neutrophils
non-eugenol periodontal dressing
Original
Patients
Periodontics
Phenols (Class of compounds)
Pigmentation disorders
platelet-rich fibrin
Platelets
Statistical analysis
Surgery
Toluidine
Wound care
Wound healing
Wounds
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c562l-ea371ae247200c6cf0790dcc63d4cd63d76863a54336e35053416a3a9ef52c703
cites
container_end_page 350
container_issue 4
container_start_page 345
container_title Journal of Indian Society of Periodontology
container_volume 23
creator Dahiya, Ritu
Blaggana, Anshu
Panwar, Vinod
Kumar, Shubham
Kathuria, Abhinav
Malik, Srijna
description Background: The platelet-rich fibrin (PRF) has proven an immense role in angiogenesis and epithelization in a wound healing process. The present study aims to ascertain PRF's beneficial role in wound healing after depigmentation surgery. Materials and Methods: A total of 12 systemically healthy controls included were divided into two groups after scalpel depigmentation procedure. PRF was prepared according to Choukroun's standard protocol. Using split-mouth design after depigmentation, one group received PRF membrane, and in second group non-eugenol periodontal dressing was placed. The participants were evaluated for visual analog scale (VAS), healing index (HI) on 3rd and 5th day. Epithelization test using toluidine blue and histological examination employing punch biopsy was done on the 5th day. Results: On statistical scale, VAS, HI, epithelization test, and histological findings were statistically significant in the two study groups. PRF group proved better epithelization test and inflammatory cell infiltration was less in PRF group which confirmed superior wound healing in the group. Conclusion: PRF membrane postdepigmentation provided satisfactory patient comfort and enhanced the wound healing cascade.
doi_str_mv 10.4103/jisp.jisp_688_18
format article
fullrecord <record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_d758009d7cbb430b8a2fb78e6599f416</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A592216373</galeid><doaj_id>oai_doaj_org_article_d758009d7cbb430b8a2fb78e6599f416</doaj_id><sourcerecordid>A592216373</sourcerecordid><originalsourceid>FETCH-LOGICAL-c562l-ea371ae247200c6cf0790dcc63d4cd63d76863a54336e35053416a3a9ef52c703</originalsourceid><addsrcrecordid>eNp1kk1v1DAQhiMEoqVw54QiISEuWRw7sZMLUqn4qFSJC0jcLK8zSbz12sF2dtXfwR9mdrctXQSK5Fgzz7wej98se1mSRVUS9m5l4rTYLZI3jSybR9kpaUVdlHVDHu_3tChp9eMkexbjihBeNYw_zU5YybgoGT3Nfl1Y44xWNleuy0cTk7d-2Ae0X08qmOhd7vt8siqBhVQEo8e8N8tgXL6BEOeYO-8KmAdw3uYTBOM77xIqdAFiNG7IEU0j5CmASmtwaSc4YMJskBpvsGYywy6hkvHuefakVzbCi9v_Wfb908dvF1-Kq6-fLy_Orwpdc2oLUEyUCmglKCGa656IlnRac9ZVusNV8IYzVVeMcWA1qVlVcsVUC31NtSDsLLs86HZereQUzFqFG-mVkfuAD4NUIRltQXYCJ0raTujlsmJk2SjaL0UDvG7bHmVR6_1Ba5qXa-g03iUoeyR6nHFmlIPfSM5pg42iwNtbgeB_zhCTXJuowVrlwM9RUsqFqITgLaKv_0JXfg4OR4VUzUpslNE_1KDwAsb1Hs_VO1F5XreUYtOCIbX4B4VfB2ujvYPeYPyo4M2DghGUTWP0dt49XDwGyQHUwccYoL8fRknkzr1yb9wH7sWSVw-HeF9wZ1cEPhyArbcJvXdt5y0Eiey189v_CktW1fLO6Ow30ZwGvQ</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2253100932</pqid></control><display><type>article</type><title>Clinical and histological comparison of platelet-rich fibrin versus non-eugenol periodontal dressing in the treatment of gingival hyperpigmentation</title><source>Publicly Available Content Database</source><source>PubMed Central</source><creator>Dahiya, Ritu ; Blaggana, Anshu ; Panwar, Vinod ; Kumar, Shubham ; Kathuria, Abhinav ; Malik, Srijna</creator><creatorcontrib>Dahiya, Ritu ; Blaggana, Anshu ; Panwar, Vinod ; Kumar, Shubham ; Kathuria, Abhinav ; Malik, Srijna</creatorcontrib><description>Background: The platelet-rich fibrin (PRF) has proven an immense role in angiogenesis and epithelization in a wound healing process. The present study aims to ascertain PRF's beneficial role in wound healing after depigmentation surgery. Materials and Methods: A total of 12 systemically healthy controls included were divided into two groups after scalpel depigmentation procedure. PRF was prepared according to Choukroun's standard protocol. Using split-mouth design after depigmentation, one group received PRF membrane, and in second group non-eugenol periodontal dressing was placed. The participants were evaluated for visual analog scale (VAS), healing index (HI) on 3rd and 5th day. Epithelization test using toluidine blue and histological examination employing punch biopsy was done on the 5th day. Results: On statistical scale, VAS, HI, epithelization test, and histological findings were statistically significant in the two study groups. PRF group proved better epithelization test and inflammatory cell infiltration was less in PRF group which confirmed superior wound healing in the group. Conclusion: PRF membrane postdepigmentation provided satisfactory patient comfort and enhanced the wound healing cascade.</description><identifier>ISSN: 0972-124X</identifier><identifier>EISSN: 0975-1580</identifier><identifier>DOI: 10.4103/jisp.jisp_688_18</identifier><identifier>PMID: 31367132</identifier><language>eng</language><publisher>India: Wolters Kluwer India Pvt. Ltd</publisher><subject>Angiogenesis ; Biopsy ; Cell division ; Comparative analysis ; Eugenol ; Fibrin ; Gingival hyperpigmentation ; Hyperpigmentation ; Inflammation ; Neutrophils ; non-eugenol periodontal dressing ; Original ; Patients ; Periodontics ; Phenols (Class of compounds) ; Pigmentation disorders ; platelet-rich fibrin ; Platelets ; Statistical analysis ; Surgery ; Toluidine ; Wound care ; Wound healing ; Wounds</subject><ispartof>Journal of Indian Society of Periodontology, 2019-07, Vol.23 (4), p.345-350</ispartof><rights>COPYRIGHT 2019 Medknow Publications and Media Pvt. Ltd.</rights><rights>2019. This work is published under https://creativecommons.org/licenses/by-nc-sa/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright: © 2019 Journal of Indian Society of Periodontology 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c562l-ea371ae247200c6cf0790dcc63d4cd63d76863a54336e35053416a3a9ef52c703</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628768/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2253100932?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31367132$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dahiya, Ritu</creatorcontrib><creatorcontrib>Blaggana, Anshu</creatorcontrib><creatorcontrib>Panwar, Vinod</creatorcontrib><creatorcontrib>Kumar, Shubham</creatorcontrib><creatorcontrib>Kathuria, Abhinav</creatorcontrib><creatorcontrib>Malik, Srijna</creatorcontrib><title>Clinical and histological comparison of platelet-rich fibrin versus non-eugenol periodontal dressing in the treatment of gingival hyperpigmentation</title><title>Journal of Indian Society of Periodontology</title><addtitle>J Indian Soc Periodontol</addtitle><description>Background: The platelet-rich fibrin (PRF) has proven an immense role in angiogenesis and epithelization in a wound healing process. The present study aims to ascertain PRF's beneficial role in wound healing after depigmentation surgery. Materials and Methods: A total of 12 systemically healthy controls included were divided into two groups after scalpel depigmentation procedure. PRF was prepared according to Choukroun's standard protocol. Using split-mouth design after depigmentation, one group received PRF membrane, and in second group non-eugenol periodontal dressing was placed. The participants were evaluated for visual analog scale (VAS), healing index (HI) on 3rd and 5th day. Epithelization test using toluidine blue and histological examination employing punch biopsy was done on the 5th day. Results: On statistical scale, VAS, HI, epithelization test, and histological findings were statistically significant in the two study groups. PRF group proved better epithelization test and inflammatory cell infiltration was less in PRF group which confirmed superior wound healing in the group. Conclusion: PRF membrane postdepigmentation provided satisfactory patient comfort and enhanced the wound healing cascade.</description><subject>Angiogenesis</subject><subject>Biopsy</subject><subject>Cell division</subject><subject>Comparative analysis</subject><subject>Eugenol</subject><subject>Fibrin</subject><subject>Gingival hyperpigmentation</subject><subject>Hyperpigmentation</subject><subject>Inflammation</subject><subject>Neutrophils</subject><subject>non-eugenol periodontal dressing</subject><subject>Original</subject><subject>Patients</subject><subject>Periodontics</subject><subject>Phenols (Class of compounds)</subject><subject>Pigmentation disorders</subject><subject>platelet-rich fibrin</subject><subject>Platelets</subject><subject>Statistical analysis</subject><subject>Surgery</subject><subject>Toluidine</subject><subject>Wound care</subject><subject>Wound healing</subject><subject>Wounds</subject><issn>0972-124X</issn><issn>0975-1580</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNp1kk1v1DAQhiMEoqVw54QiISEuWRw7sZMLUqn4qFSJC0jcLK8zSbz12sF2dtXfwR9mdrctXQSK5Fgzz7wej98se1mSRVUS9m5l4rTYLZI3jSybR9kpaUVdlHVDHu_3tChp9eMkexbjihBeNYw_zU5YybgoGT3Nfl1Y44xWNleuy0cTk7d-2Ae0X08qmOhd7vt8siqBhVQEo8e8N8tgXL6BEOeYO-8KmAdw3uYTBOM77xIqdAFiNG7IEU0j5CmASmtwaSc4YMJskBpvsGYywy6hkvHuefakVzbCi9v_Wfb908dvF1-Kq6-fLy_Orwpdc2oLUEyUCmglKCGa656IlnRac9ZVusNV8IYzVVeMcWA1qVlVcsVUC31NtSDsLLs86HZereQUzFqFG-mVkfuAD4NUIRltQXYCJ0raTujlsmJk2SjaL0UDvG7bHmVR6_1Ba5qXa-g03iUoeyR6nHFmlIPfSM5pg42iwNtbgeB_zhCTXJuowVrlwM9RUsqFqITgLaKv_0JXfg4OR4VUzUpslNE_1KDwAsb1Hs_VO1F5XreUYtOCIbX4B4VfB2ujvYPeYPyo4M2DghGUTWP0dt49XDwGyQHUwccYoL8fRknkzr1yb9wH7sWSVw-HeF9wZ1cEPhyArbcJvXdt5y0Eiey189v_CktW1fLO6Ow30ZwGvQ</recordid><startdate>20190701</startdate><enddate>20190701</enddate><creator>Dahiya, Ritu</creator><creator>Blaggana, Anshu</creator><creator>Panwar, Vinod</creator><creator>Kumar, Shubham</creator><creator>Kathuria, Abhinav</creator><creator>Malik, Srijna</creator><general>Wolters Kluwer India Pvt. Ltd</general><general>Medknow Publications and Media Pvt. Ltd</general><general>Medknow Publications &amp; Media Pvt. Ltd</general><general>Wolters Kluwer - Medknow</general><general>Wolters Kluwer Medknow Publications</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>PADUT</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20190701</creationdate><title>Clinical and histological comparison of platelet-rich fibrin versus non-eugenol periodontal dressing in the treatment of gingival hyperpigmentation</title><author>Dahiya, Ritu ; Blaggana, Anshu ; Panwar, Vinod ; Kumar, Shubham ; Kathuria, Abhinav ; Malik, Srijna</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c562l-ea371ae247200c6cf0790dcc63d4cd63d76863a54336e35053416a3a9ef52c703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Angiogenesis</topic><topic>Biopsy</topic><topic>Cell division</topic><topic>Comparative analysis</topic><topic>Eugenol</topic><topic>Fibrin</topic><topic>Gingival hyperpigmentation</topic><topic>Hyperpigmentation</topic><topic>Inflammation</topic><topic>Neutrophils</topic><topic>non-eugenol periodontal dressing</topic><topic>Original</topic><topic>Patients</topic><topic>Periodontics</topic><topic>Phenols (Class of compounds)</topic><topic>Pigmentation disorders</topic><topic>platelet-rich fibrin</topic><topic>Platelets</topic><topic>Statistical analysis</topic><topic>Surgery</topic><topic>Toluidine</topic><topic>Wound care</topic><topic>Wound healing</topic><topic>Wounds</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dahiya, Ritu</creatorcontrib><creatorcontrib>Blaggana, Anshu</creatorcontrib><creatorcontrib>Panwar, Vinod</creatorcontrib><creatorcontrib>Kumar, Shubham</creatorcontrib><creatorcontrib>Kathuria, Abhinav</creatorcontrib><creatorcontrib>Malik, Srijna</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Research Library China</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>Journal of Indian Society of Periodontology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dahiya, Ritu</au><au>Blaggana, Anshu</au><au>Panwar, Vinod</au><au>Kumar, Shubham</au><au>Kathuria, Abhinav</au><au>Malik, Srijna</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical and histological comparison of platelet-rich fibrin versus non-eugenol periodontal dressing in the treatment of gingival hyperpigmentation</atitle><jtitle>Journal of Indian Society of Periodontology</jtitle><addtitle>J Indian Soc Periodontol</addtitle><date>2019-07-01</date><risdate>2019</risdate><volume>23</volume><issue>4</issue><spage>345</spage><epage>350</epage><pages>345-350</pages><issn>0972-124X</issn><eissn>0975-1580</eissn><abstract>Background: The platelet-rich fibrin (PRF) has proven an immense role in angiogenesis and epithelization in a wound healing process. The present study aims to ascertain PRF's beneficial role in wound healing after depigmentation surgery. Materials and Methods: A total of 12 systemically healthy controls included were divided into two groups after scalpel depigmentation procedure. PRF was prepared according to Choukroun's standard protocol. Using split-mouth design after depigmentation, one group received PRF membrane, and in second group non-eugenol periodontal dressing was placed. The participants were evaluated for visual analog scale (VAS), healing index (HI) on 3rd and 5th day. Epithelization test using toluidine blue and histological examination employing punch biopsy was done on the 5th day. Results: On statistical scale, VAS, HI, epithelization test, and histological findings were statistically significant in the two study groups. PRF group proved better epithelization test and inflammatory cell infiltration was less in PRF group which confirmed superior wound healing in the group. Conclusion: PRF membrane postdepigmentation provided satisfactory patient comfort and enhanced the wound healing cascade.</abstract><cop>India</cop><pub>Wolters Kluwer India Pvt. Ltd</pub><pmid>31367132</pmid><doi>10.4103/jisp.jisp_688_18</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0972-124X
ispartof Journal of Indian Society of Periodontology, 2019-07, Vol.23 (4), p.345-350
issn 0972-124X
0975-1580
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_d758009d7cbb430b8a2fb78e6599f416
source Publicly Available Content Database; PubMed Central
subjects Angiogenesis
Biopsy
Cell division
Comparative analysis
Eugenol
Fibrin
Gingival hyperpigmentation
Hyperpigmentation
Inflammation
Neutrophils
non-eugenol periodontal dressing
Original
Patients
Periodontics
Phenols (Class of compounds)
Pigmentation disorders
platelet-rich fibrin
Platelets
Statistical analysis
Surgery
Toluidine
Wound care
Wound healing
Wounds
title Clinical and histological comparison of platelet-rich fibrin versus non-eugenol periodontal dressing in the treatment of gingival hyperpigmentation
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T08%3A23%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical%20and%20histological%20comparison%20of%20platelet-rich%20fibrin%20versus%20non-eugenol%20periodontal%20dressing%20in%20the%20treatment%20of%20gingival%20hyperpigmentation&rft.jtitle=Journal%20of%20Indian%20Society%20of%20Periodontology&rft.au=Dahiya,%20Ritu&rft.date=2019-07-01&rft.volume=23&rft.issue=4&rft.spage=345&rft.epage=350&rft.pages=345-350&rft.issn=0972-124X&rft.eissn=0975-1580&rft_id=info:doi/10.4103/jisp.jisp_688_18&rft_dat=%3Cgale_doaj_%3EA592216373%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c562l-ea371ae247200c6cf0790dcc63d4cd63d76863a54336e35053416a3a9ef52c703%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2253100932&rft_id=info:pmid/31367132&rft_galeid=A592216373&rfr_iscdi=true